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胸段硬脊膜内髓外表皮样肿瘤:现代脊柱外科中经典蛛网膜下腔显微手术解剖结构对切除的相关性。技术说明及文献综述

Thoracic Intradural-Extramedullary Epidermoid Tumor: The Relevance for Resection of Classic Subarachnoid Space Microsurgical Anatomy in Modern Spinal Surgery. Technical Note and Review of the Literature.

作者信息

Barbagallo Giuseppe M V, Maione Massimiliano, Raudino Giuseppe, Certo Francesco

机构信息

Department of Neurological Surgery, Policlinico "G. Rodolico" University Hospital, Catania, Italy.

Department of Neurological Surgery, Policlinico "G. Rodolico" University Hospital, Catania, Italy.

出版信息

World Neurosurg. 2017 Dec;108:54-61. doi: 10.1016/j.wneu.2017.08.078. Epub 2017 Aug 24.

Abstract

BACKGROUND

Intradural epidermoid tumors of the spinal cord are commonly associated with spinal cord dysraphism or invasive procedures. We report the particular relationships between spinal subarachnoid compartments and thoracic intradural-extramedullary epidermoid tumor, highlighting the relevant anatomic changes that may influence microsurgery.

METHODS

A 40-year-old woman from compressive myelopathy owing to a thoracic epidermoid tumor extending from T3 to T4 and not associated with spina bifida, trauma, previous surgery, or lumbar spinal puncture underwent microsurgical excision. Accurate tumor membrane dissection, respecting spinal arachnoidal compartments, was performed. Reposition of a laminoplasty plateau helped in restoring thoracic spine anatomic integrity.

RESULTS

Safe gross total tumor resection was achieved. Complete neurologic recovery as well as absence of recurrent tumor was documented at 4-year follow-up. A literature review revealed only 2 other cases of "isolated" thoracic spine epidermoid tumor. However, description of the relationship between tumor membranes and spinal subarachnoid compartments was not available in either case.

CONCLUSIONS

A thorough knowledge of spinal subarachnoid space anatomy is helpful to distinguish between tumor membranes and arachnoidal planes and to achieve a safe and complete resection to avoid recurrences.

摘要

背景

脊髓硬膜内表皮样肿瘤通常与脊髓发育异常或侵入性操作有关。我们报告了脊髓蛛网膜下腔各间隙与胸段硬膜内髓外表皮样肿瘤之间的特殊关系,强调了可能影响显微手术的相关解剖学变化。

方法

一名40岁女性因胸段表皮样肿瘤导致脊髓受压,肿瘤从T3延伸至T4,与脊柱裂、外伤、既往手术或腰椎穿刺无关,接受了显微手术切除。手术过程中准确地进行肿瘤包膜分离,同时注意保护脊髓蛛网膜下腔各间隙。通过椎板成形术复位钢板有助于恢复胸椎的解剖完整性。

结果

成功实现了肿瘤的安全全切。4年随访结果显示患者神经功能完全恢复,且无肿瘤复发。文献回顾仅发现另外2例“孤立性”胸段脊柱表皮样肿瘤病例。然而,这两例均未描述肿瘤包膜与脊髓蛛网膜下腔各间隙之间的关系。

结论

深入了解脊髓蛛网膜下腔的解剖结构有助于区分肿瘤包膜与蛛网膜层面,从而实现安全、完整的切除,避免肿瘤复发。

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