Liu Jianxue, Zhang Yaoren, Ji Yonghao, Wan Qinyun, Dun Guoliang
Department of Infectious Disease, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Shaanxi 710061, China; Department of Ultrasonography, Baoji Central Hospital, Baoji 721008, China.
Department of Ultrasonography, Baoji Central Hospital, Baoji 721008, China.
Clin Imaging. 2018 May-Jun;49:187-192. doi: 10.1016/j.clinimag.2018.03.019. Epub 2018 Mar 29.
The aim of this study is to discuss the value of ultrasound-based shear wave™ elastography (SWE) in diffuse thyroid disease (DTD).
Thyroid stiffness in 154 patients with DTD and 30 normal subjects was measured by SWE. The serum indicators of all subjects were detected.
The area under the receiver operating characteristic (AUROC) curve for DTD by SWE was 0.852. The AUROCs of SWE for differentiating chronic autoimmune thyroiditis (CAT) from Graves' disease (GD) and subacute thyroiditis (SAT) were 0.549 and 0.989, respectively. The AUROCs for distinguishing GD from SAT by SWE and the fT3/fT4 ratio were 0.975 and 0.713, respectively.
SWE aids in the diagnosis of DTD, and SWE is superior to the fT3/fT4 ratio for distinguishing GD from SAT. However, SWE was unsuitable for differentiating CAT from GD.
本研究旨在探讨基于超声的剪切波弹性成像（SWE）在弥漫性甲状腺疾病（DTD）中的价值。
采用SWE测量154例DTD患者和30例正常受试者的甲状腺硬度。检测所有受试者的血清指标。
SWE诊断DTD的受试者操作特征曲线（AUROC）下面积为0.852。SWE鉴别慢性自身免疫性甲状腺炎（CAT）与Graves病（GD）和亚急性甲状腺炎（SAT）的AUROC分别为0.549和0.989。SWE和fT3/fT4比值鉴别GD与SAT的AUROC分别为0.975和0.713。
SWE有助于DTD的诊断，且在鉴别GD与SAT方面SWE优于fT3/fT4比值。然而，SWE不适用于鉴别CAT与GD。
