Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer.
作者信息
Tan Shuangyan, Gou Qiheng, Pu Wenchen, Guo Chenglin, Yang Yun, Wu Ke, Liu Yaxin, Liu Lunxu, Wei Yu-Quan, Peng Yong
机构信息
Department of Thoracic Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, 610041, Chengdu, China.
CAS Key Lab for Computational Biology, CAS Center for Excellence in Molecular Cell Science, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.
出版信息
Cell Res. 2018 Jun;28(6):693-695. doi: 10.1038/s41422-018-0033-7. Epub 2018 Apr 8.
Abstract
摘要
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本文引用的文献
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Non-small-cell lung cancer.非小细胞肺癌。
Nat Rev Dis Primers. 2015 May 21;1:15009. doi: 10.1038/nrdp.2015.9.
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Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations.致癌融合环状 RNA 来源于与癌症相关的染色体易位。
Cell. 2016 Apr 7;165(2):289-302. doi: 10.1016/j.cell.2016.03.020. Epub 2016 Mar 31.
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The biogenesis and emerging roles of circular RNAs.环状 RNA 的生物发生和新兴作用。
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Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.环状RNA在外泌体中富集且稳定：一种有前景的癌症诊断生物标志物。
Cell Res. 2015 Aug;25(8):981-4. doi: 10.1038/cr.2015.82. Epub 2015 Jul 3.
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Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.哺乳动物脑中的环状 RNA 丰度高、保守且表达具有动态性。
Mol Cell. 2015 Jun 4;58(5):870-85. doi: 10.1016/j.molcel.2015.03.027. Epub 2015 Apr 23.
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EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.EML4-ALK融合基因与ALK激酶抑制剂在肺癌中的疗效
Clin Cancer Res. 2008 Jul 1;14(13):4275-83. doi: 10.1158/1078-0432.CCR-08-0168.
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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.非小细胞肺癌中转化型EML4-ALK融合基因的鉴定。
Nature. 2007 Aug 2;448(7153):561-6. doi: 10.1038/nature05945. Epub 2007 Jul 11.
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