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机器人盆腔手术期间的限制性液体策略会抑制术中眼压升高吗?

Does Restrictive Fluid Strategy during Robotic Pelvic Surgeries Obtund Intraoperative Rise in Intraocular Pressure?

作者信息

Tosh Pulak, Krishnankutty Saritha Valsala, Rajan Sunil, Nair Hema Muraleedharan, Puthanveettil Nitu, Kumar Lakshmi

机构信息

Department of Anaesthesiology, Amrita Institute of Medical Sciences, Amrita University, Kochi, India.

Department of Ophthalmology, Government Medical College, Kottayam, Kerala, India.

出版信息

Anesth Essays Res. 2018 Jan-Mar;12(1):155-158. doi: 10.4103/aer.AER_144_17.

Abstract

BACKGROUND

Robotic pelvic surgeries require steep Trendelenburg position which may result in rise in intraocular pressure (IOP).

AIM

The aim of this study was to compare the changes that occur in IOP during robotic pelvic surgeries in steep Trendelenburg position with a restrictive intravenous fluid administration.

SETTINGS AND DESIGN

This prospective observational study was conducted in a tertiary care institution.

SUBJECTS AND METHODS

Twenty consenting patients scheduled for pelvic robotic gynecological surgeries were enrolled. All patients received general anesthesia following a standardized protocol. IOP was measured before induction of anesthesia, immediately after induction and intubation, at the end of surgery immediately after making the patient supine and immediately after extubation. Ringer's lactate was administered intravenously at a rate of 4 mL/kg/h targeting a mean arterial pressure of >65 mmHg and urine output of >0.5 mL/kg/h.

STATISTICAL ANALYSIS USED

Paired -test was used in this study.

RESULTS

There was a fall in IOP soon after induction from baseline which was not significant. Immediately, following intubation, there was a significant rise in IOP. At the end of surgery, though IOP remained high, it was not statistically significant. However, following extubation, IOP rose further and the difference from the baseline became statistically significant. Although there was a moderate increase in peak airway pressure and highest EtCO levels during Trendelenburg from baseline values, the differences were statistically insignificant.

CONCLUSION

During robotic pelvic surgeries, adopting a restrictive intravenous fluid strategy with the maintenance of normal end-tidal carbon dioxide levels could abate effects of steep Trendelenburg position on IOP.

摘要

背景

机器人辅助盆腔手术需要采用头低脚高位,这可能导致眼内压(IOP)升高。

目的

本研究旨在比较在头低脚高位进行机器人辅助盆腔手术时,采用限制性静脉输液管理与不采用该管理方式下眼内压的变化情况。

设置与设计

这是一项在三级医疗机构进行的前瞻性观察性研究。

研究对象与方法

纳入20例同意接受盆腔机器人辅助妇科手术的患者。所有患者均按照标准化方案接受全身麻醉。在麻醉诱导前、诱导及插管后即刻、手术结束患者平卧后即刻以及拔管后即刻测量眼内压。以4 mL/kg/h的速率静脉输注乳酸林格氏液,目标是平均动脉压>65 mmHg且尿量>0.5 mL/kg/h。

统计分析方法

本研究采用配对t检验。

结果

诱导后眼内压较基线值即刻下降,但差异不显著。插管后即刻,眼内压显著升高。手术结束时,尽管眼内压仍处于较高水平,但差异无统计学意义。然而,拔管后,眼内压进一步升高,与基线值的差异具有统计学意义。尽管在头低脚高位时,气道峰压和呼气末二氧化碳分压(EtCO)的最高值较基线值有适度升高,但差异无统计学意义。

结论

在机器人辅助盆腔手术中,采用限制性静脉输液策略并维持正常的呼气末二氧化碳水平,可减轻头低脚高位对眼内压的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc2a/5872854/ad3da6bd8d22/AER-12-155-g002.jpg

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