Thongsawad Sangutid, Khamfongkhruea Chirasak, Tannanonta Chirapha
Department of Radiation Oncology, Chulabhorn Hospital, Bangkok, Thailand.
J Med Phys. 2018 Jan-Mar;43(1):52-57. doi: 10.4103/jmp.JMP_75_17.
The aim of this study was to investigate the potential of jaw tracking with the volumetric-modulated arc therapy (VMAT) to reduce the normal tissue dose. Plans of nasopharynx, lung, and prostate cancers (10 plans for each) were used to perform VMAT with and without jaw tracking. The dose reduction was evaluated in terms of organ doses and integral doses. Organ-dose reduction with jaw tracking was statistically significant in the volume receiving a dose of 5 Gy (V) of bladder, rectum, and lung, the volume receiving a dose of 10 Gy (V) of bladder, rectum, and lung, and the mean dose of lung ( < 0.05). Integral-dose reduction with jaw tracking was statistically significant in almost all the treatment plans ( < 0.05). For organ-dose reduction, jaw tracking in VMAT plan was effective in reducing V and V. For integral-dose reduction, jaw tracking in VMAT plan is an efficient method for decreasing V.
本研究的目的是探讨容积调强弧形放疗（VMAT）进行颌骨追踪以降低正常组织剂量的潜力。使用鼻咽癌、肺癌和前列腺癌的计划（每种10个计划）进行有和没有颌骨追踪的VMAT。从器官剂量和积分剂量方面评估剂量降低情况。在膀胱、直肠和肺接受5 Gy剂量（V）的体积、膀胱、直肠和肺接受10 Gy剂量（V）的体积以及肺的平均剂量方面，颌骨追踪导致的器官剂量降低具有统计学意义（<0.05）。在几乎所有治疗计划中，颌骨追踪导致的积分剂量降低具有统计学意义（<0.05）。对于器官剂量降低，VMAT计划中的颌骨追踪在降低V和V方面有效。对于积分剂量降低，VMAT计划中的颌骨追踪是降低V的有效方法。
