Jafari Seyed Ali, Kiani Mohammad Ali, Kianifar Hamid Reza, Mansooripour Mohammad, Heidari Elahe, Khalesi Maryam
MD, Associate Professor, Department of Pediatric Gastroenterology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
MD, Professor, Allergy research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Electron Physician. 2018 Feb 25;10(2):6341-6345. doi: 10.19082/6341. eCollection 2018 Feb.
Gastrointestinal (GI) bleeding, which has several clinical manifestation and origins, is known as one of the most life-threatening events in children. Several etiologies have been suggested for GI bleeding.
To determine the most important causes of GI bleeding in children referred to Ghaem Hospital and Dr. Sheikh Hospital, Mashhad, Iran.
In this cross-sectional study, after obtaining written informed consent of their parents, 113 patients aging from newborn infants to 18-year-old children with GI bleeding admitted to Ghaem Hospital and Dr. Sheikh hospital were enrolled in this study from June 2012 to June 2014. After performing routine diagnostic and therapeutic procedures, a checklist containing all necessary information including demographic data, clinical history of patients, endoscopy and pathology findings, clinical and preclinical information were collected. The data were then analyzed using Statistical Package for the Social Sciences (SPSS) version 16.
Of a total 113 study children, 61 (54%) were male and 52 (46%) were female. The results of this study showed that the most important causes of bleeding in upper GI among all admitted patients were prolapse gastropathy (18.6%), esophagitis (15.9%) and esophageal varices, gastritis, and coagulopathy (7.1% for each). The main causes of lower GI bleeding were polyp (32.5%), chronic nonspecific colitis (20.7%), and proctitis (18.2%).
Findings of this study indicated that prolapse gastropathy and esophagitis are more prevalent causes of upper GI bleeding. Furthermore, esophageal varices were more common in children older than 13 years. Polyp, chronic nonspecific colitis and proctitis are the most prevalent causes of lower GI bleeding.
胃肠道（GI）出血有多种临床表现和病因，是儿童最危及生命的事件之一。关于胃肠道出血的病因有多种说法。
确定转诊至伊朗马什哈德的加姆医院和谢赫医院的儿童胃肠道出血的最重要原因。
在这项横断面研究中，在获得患儿父母的书面知情同意后，纳入了2012年6月至2014年6月期间入住加姆医院和谢赫医院的113例从新生儿到18岁患有胃肠道出血的患者。在进行常规诊断和治疗程序后，收集了一份包含所有必要信息的清单，包括人口统计学数据、患者临床病史、内镜检查和病理检查结果、临床和临床前信息。然后使用社会科学统计软件包（SPSS）16版对数据进行分析。
在总共113例研究儿童中，61例（54%）为男性，52例（46%）为女性。该研究结果表明，所有入院患者中上消化道出血的最重要原因是胃黏膜脱垂（18.6%）、食管炎（15.9%）以及食管静脉曲张、胃炎和凝血功能障碍（各占7.1%）。下消化道出血的主要原因是息肉（32.5%）、慢性非特异性结肠炎（20.7%）和直肠炎（18.2%）。
本研究结果表明，胃黏膜脱垂和食管炎是上消化道出血更常见的原因。此外，食管静脉曲张在13岁以上儿童中更为常见。息肉、慢性非特异性结肠炎和直肠炎是下消化道出血最常见的原因。
