联合肝脏分隔和门静脉结扎分期肝切除术（ALPPS），随后行左半肝切除术及胰腺神经内分泌肿瘤（PNET）的Whipple手术。
Combined associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) followed by left trisectionectomy and Whipple operation for PNET.
作者信息
Ji Ren, Zuo Shi, Qiu Siyuan, Li Ping, Chan Albert, Sharr William, Lo Chung Mau
机构信息
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University of Hong Kong-Shenzhen Hospital, Shenzhen 518053, China.
Division of Pathology, University of Hong Kong-Shenzhen Hospital, Shenzhen 518053, China.
出版信息
Gland Surg. 2018 Feb;7(1):47-53. doi: 10.21037/gs.2017.11.15.
Abstract
Pancreatic neuroendocrine tumor (PNET) is slow-growing, and account only for 2% of all pancreatic primary tumors. Surgical resection is still the only curative treatment for PNET patients. Unfortunately, most of PNETs was found with unresectable multiple liver metastases and extrahepatic metastasis as their characteristics of non-functional and asymptomatic. With advances in liver surgery in these years, especially combined associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), provide a new curative surgical treatment for PNET with liver metastases patient. Here we report a PNET with multiple liver metastases case underwent ALPPS (followed by left trisectionectomy) and Whipple operation within one-stage.
摘要
胰腺神经内分泌肿瘤（PNET）生长缓慢，仅占所有胰腺原发性肿瘤的2%。手术切除仍然是PNET患者唯一的治愈性治疗方法。不幸的是，大多数PNET以不可切除的多发肝转移和肝外转移为特征，表现为无功能且无症状。近年来随着肝脏手术的进展，尤其是联合肝脏分隔和门静脉结扎分期肝切除术（ALPPS），为伴有肝转移的PNET患者提供了一种新的治愈性手术治疗方法。在此我们报告1例伴有多发肝转移的PNET患者一期接受了ALPPS（随后行左半肝切除术）和Whipple手术。
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