骨肉瘤：一篇综述
Osteosarcoma: a comprehensive review.
作者信息
Misaghi Amirhossein, Goldin Amanda, Awad Moayd, Kulidjian Anna A
机构信息
Department of Orthopaedic Surgery, University of California San Diego, San Diego, CA, USA.
Department of Orthopaedic Surgery, University of California San Diego, San Diego, CA, USA - School of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
出版信息
SICOT J. 2018;4:12. doi: 10.1051/sicotj/2017028. Epub 2018 Apr 9.
Abstract
Osteosarcoma (OS) is a relatively rare tumor of bone with a worldwide incidence of 3.4 cases per million people per year. For most of the twentieth century, five-year survival rates for classic OS were very low. In the 1970s, the introduction of adjuvant chemotherapy in the treatment of OS increased survival rates dramatically. The current article reviews the various types of OS and analyzes the clinical and histological features. We also examine historical and current literature to present a succinct review of methods for diagnosis and staging, as well as treatment, and we also discuss some of the future directions of treatment.
摘要
骨肉瘤（OS）是一种相对罕见的骨肿瘤，全球发病率为每年每百万人中有3.4例。在20世纪的大部分时间里，经典骨肉瘤的五年生存率非常低。20世纪70年代，辅助化疗引入骨肉瘤治疗后，生存率显著提高。本文回顾了骨肉瘤的各种类型，并分析了其临床和组织学特征。我们还查阅了历史和当前文献，以简要综述诊断、分期以及治疗方法，并且我们也讨论了一些未来的治疗方向。
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