Clin Nucl Med. 2018 Jun;43(6):e178-e179. doi: 10.1097/RLU.0000000000002089.
Fenpyroximate is a widely used acaricide. Its main action is to inhibit the mitochondrial respiratory chain. Chronic exposure to fenpyroximate is associated with dopaminergic cell loss and parkinsonism; however, to date, there has not been a reported case of parkinsonism as a result of acute fenpyroximate intoxication. Here, we report a 58-year-old man who developed parkinsonism after deliberate fenpyroximate intoxication, but with normal presynaptic I-Ioflupane SPECT image.
呋虫胺是一种广泛使用的杀螨剂，其主要作用是抑制线粒体呼吸链。慢性暴露于呋虫胺会导致多巴胺能神经元丧失和帕金森病；然而，迄今为止，尚未有报告称急性呋虫胺中毒会导致帕金森病。在此，我们报告了一例 58 岁男性，因故意摄入呋虫胺而出现帕金森病，但 I-碘代异丙托品 SPECT 图像正常。
