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成功治疗表现为巨大、不愈合臀部溃疡的先天性/婴儿纤维肉瘤。

Successful management of congenital/infantile fibrosarcoma presenting as large, non-healing buttock ulceration.

作者信息

Sowash Madeleine G, Mosojane Karen Itumeleng, Anderson Alan R, Kovari Carrie L, Williams Victoria L

机构信息

Columbia University College of Physicians and Surgeons, New York, New York, Botswana-University of Pennsylvania Partnership, Gaborone, Botswana, Ministry of Health of Botswana, Gaborone, Botswana,.

出版信息

Dermatol Online J. 2018 Feb 15;24(2):13030/qt6z85r7vh.

Abstract

A two-year-old boy presented with a large, non-healing ulceration on his left buttock, which was originally noted as a brown patch present at birth. Punch skin biopsy was performed and histopathology revealed an atypical, pleomorphic, spindled proliferation in whorled fascicles replacing the dermis and trapping fat in the subcutis, consistent with a diagnosis of congenital/infantile fibrosarcoma. No evidence of metastatic spread was seen on imaging. The tumor was initially deemed unresectable owing to extent of local invasion. Neo-adjuvant chemotherapy caused significant tumor shrinkage and the patient underwent complete resection.

摘要

一名两岁男孩左侧臀部出现一个大的、不愈合的溃疡,最初发现是出生时就存在的褐色斑。进行了皮肤打孔活检,组织病理学显示有非典型的、多形性的、梭形细胞呈漩涡状束状增生,取代真皮并包绕皮下脂肪,符合先天性/婴儿型纤维肉瘤的诊断。影像学检查未发现转移扩散的证据。由于局部侵犯范围,该肿瘤最初被认为无法切除。新辅助化疗使肿瘤显著缩小,患者接受了完整切除。

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