Kimura C, Kitamura T, Sugihara T
Department of Plastic and Reconstructive Surgery, Hakodate Central General Hospital, Japan.
J Dermatol. 1998 Nov;25(11):735-41. doi: 10.1111/j.1346-8138.1998.tb02493.x.
Congenital infantile fibrosarcoma is a rare soft-tissue malignant tumor that usually presents as a mass involving the arm or leg. We report a case of congenital fibrosarcoma on the right hand of a newborn infant. The patient was a 12-day-old male. From the time of delivery, he had a red tumor on his dorsal right hand. The tumor was initially associated with bleeding within a hemangioma and compressed. The course was observed. It appeared that the tumor might be malignant because it increased in size to 10 x 8 x 3 cm, and ulceration and bleeding appeared on the surface after 10 days. A biopsy suggested a fibrosarcoma. The tumor was resected 32 days after birth at the narrow margin in consideration of preservation of function. However, a recurrence was observed under the graft after 2 weeks and another resection was performed. Because the tumor had passed through the interosseous muscle and invaded the palm of the hand, the middle finger, ring finger, and little finger had to be amputated. One year and 7 months postoperatively, no recurrence or metastasis has been observed.
先天性婴儿纤维肉瘤是一种罕见的软组织恶性肿瘤，通常表现为累及手臂或腿部的肿块。我们报告一例新生儿右手先天性纤维肉瘤病例。该患者为一名12日龄男婴。自出生时起，其右手背就有一个红色肿瘤。该肿瘤最初与血管瘤内出血有关且受到压迫，遂对病程进行观察。由于肿瘤大小增至10×8×3厘米，且10天后表面出现溃疡和出血，似乎该肿瘤可能为恶性。活检提示为纤维肉瘤。考虑到功能保留，在出生32天后对肿瘤进行了窄切缘切除。然而，2周后在移植部位下方观察到复发，遂再次进行切除。由于肿瘤已穿过骨间肌并侵犯手掌，不得不将中指、无名指和小指截肢。术后1年7个月，未观察到复发或转移。
