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微创手术与加速康复时代的机械性及口服抗生素肠道准备

Mechanical and Oral Antibiotic Bowel Preparation in the Era of Minimally Invasive Surgery and Enhanced Recovery.

作者信息

Yost Mark T, Jolissaint Joshua S, Fields Adam C, Whang Edward E

机构信息

1 Harvard Medical School , Boston, Massachusetts.

2 Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts.

出版信息

J Laparoendosc Adv Surg Tech A. 2018 May;28(5):491-495. doi: 10.1089/lap.2018.0072. Epub 2018 Apr 9.

Abstract

INTRODUCTION

In the modern era of minimally invasive colorectal surgery and enhanced recovery pathways, the value of preoperative bowel preparation remains debated. In this review, we evaluate evidence regarding the use of mechanical bowel preparation (MBP) and oral antibiotic bowel preparation to make recommendations for their application in contemporary practice.

METHODS

We searched the PubMed database through December 2017 for relevant randomized controlled trials, Cochrane Reviews, American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database studies, and other reviews pertaining to MBP and oral antibiotic bowel preparation in elective colorectal surgery and conducted a narrative review.

RESULTS

The combination of MBP and oral antibiotics reduces the incidence of surgical site infection, anastomotic leak, and postoperative sepsis. MBP improves laparoscopic surgical viewing and facilitates intraoperative manipulation of the bowel in minimally invasive surgery.

CONCLUSION

Based on existing data, we recommend that preoperative care includes MBP and oral antibiotics in elective minimally invasive colorectal surgery.

摘要

引言

在微创结直肠手术和加速康复途径的现代时代,术前肠道准备的价值仍存在争议。在本综述中,我们评估了关于使用机械肠道准备(MBP)和口服抗生素肠道准备的证据,以便为它们在当代实践中的应用提出建议。

方法

我们检索了截至2017年12月的PubMed数据库,以查找相关的随机对照试验、Cochrane综述、美国外科医师学会国家外科质量改进计划(ACS-NSQIP)数据库研究,以及其他与择期结直肠手术中MBP和口服抗生素肠道准备相关的综述,并进行了叙述性综述。

结果

MBP与口服抗生素联合使用可降低手术部位感染、吻合口漏和术后脓毒症的发生率。MBP可改善腹腔镜手术视野,并有助于微创手术中肠道的术中操作。

结论

基于现有数据,我们建议在择期微创结直肠手术的术前护理中包括MBP和口服抗生素。

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