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关于外科手术中抗生素预防的六个长期存在的问题。

Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery.

作者信息

Sartelli Massimo, Boermeester Marja A, Cainzos Miguel, Coccolini Federico, de Jonge Stijn W, Rasa Kemal, Dellinger E Patchen, McNamara Deborah A, Fry Donald E, Cui Yunfeng, Delibegovic Samir, Demetrashvili Zaza, De Simone Belinda, Gkiokas George, Hardcastle Timothy C, Itani Kamal M F, Isik Arda, Labricciosa Francesco Maria, Lohsiriwat Varut, Marwah Sanjay, Pintar Tadeja, Rickard Jennifer, Shelat Vishal G, Catena Fausto, Barie Philip S

机构信息

Department of Surgery, Macerata Hospital, 62100 Macerata, Italy.

Department of Surgery, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.

出版信息

Antibiotics (Basel). 2023 May 15;12(5):908. doi: 10.3390/antibiotics12050908.

Abstract

Surgical site infections (SSIs) are the most common adverse event occurring in surgical patients. Optimal prevention of SSIs requires the bundled integration of a variety of measures before, during, and after surgery. Surgical antibiotic prophylaxis (SAP) is an effective measure for preventing SSIs. It aims to counteract the inevitable introduction of bacteria that colonize skin or mucosa into the surgical site during the intervention. This document aims to guide surgeons in appropriate administration of SAP by addressing six key questions. The expert panel identifies a list of principles in response to these questions that every surgeon around the world should always respect in administering SAP.

摘要

手术部位感染(SSIs)是外科手术患者中最常见的不良事件。最佳预防手术部位感染需要在手术前、手术中和手术后综合采取多种措施。外科手术预防性抗生素应用(SAP)是预防手术部位感染的有效措施。其目的是对抗在手术过程中皮肤或黏膜定植菌不可避免地进入手术部位的情况。本文档旨在通过回答六个关键问题,指导外科医生合理应用外科手术预防性抗生素。专家小组针对这些问题确定了一系列原则,世界各地的每位外科医生在应用外科手术预防性抗生素时都应始终遵循这些原则。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81ff/10215114/035d81db4a27/antibiotics-12-00908-g001.jpg

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