Maier W, Buller R, Philipp M, Heuser I
Department of Psychiatry, University of Mainz, F.R.G.
J Affect Disord. 1988 Jan-Feb;14(1):61-8. doi: 10.1016/0165-0327(88)90072-9.
The Hamilton Anxiety Scale (HAM-A) was tested for reliability and validity in two different samples, one sample (n = 97) defined by anxiety disorders, the other sample (n = 101) defined by depressive disorders. The reliability and the concurrent validity of the HAM-A and its subscales proved to be sufficient. Internal validity tested by latent structure analysis was insufficient. The major problems with the HAM-A are that (1) anxiolytic and antidepressant effects cannot be clearly distinguished; (2) the subscale of somatic anxiety is strongly related to somatic side effects. The applicability of the HAM-A in anxiolytic treatment studies is therefore limited. More specific anxiety scales are needed.
在两个不同样本中对汉密尔顿焦虑量表（HAM - A）进行了信效度检验，一个样本（n = 97）由焦虑症患者组成，另一个样本（n = 101）由抑郁症患者组成。HAM - A及其分量表的信度和同时效度被证明是足够的。通过潜在结构分析检验的内部效度不足。HAM - A的主要问题在于：（1）抗焦虑和抗抑郁作用无法清晰区分；（2）躯体焦虑分量表与躯体副作用密切相关。因此，HAM - A在抗焦虑治疗研究中的适用性有限。需要更具特异性的焦虑量表。
