Xu Ling, Ding Wantao, Guo Hui
Department of Clinical Psychology, Wenzhou Seventh People's Hospital, Wenzhou, China.
Department of Psychiatric Rehabilitation, Wenzhou Seventh People's Hospital, Wenzhou, China.
Front Psychol. 2025 Jul 21;16:1520448. doi: 10.3389/fpsyg.2025.1520448. eCollection 2025.
Primary insomnia is a common and complex disorder characterized by a range of symptoms and consequences of varying severity. Long-term sleep disturbances can lead to anxiety, depression and cognitive dysfunctions. This study aimed to investigate the relationship between emotional changes and cognitive dysfunction in patients with primary insomnia and to explore the factors influencing the disorder.
The study participants included 40 patients with primary insomnia diagnosed by the International Classification of Sleep Disorders-3 and 48 healthy controls from the Seventh People's Hospital of Wenzhou. The Pittsburgh Sleep Quality Index, Montreal Cognitive Assessment, Hamilton Anxiety Scale and Hamilton Depression Scale were used to assess clinical symptoms. -tests, chi-square tests, Pearson correlation and network analysis were used to examine the mutual relationship between emotional symptoms and cognitive function in participants with primary insomnia.
Both immediate and delayed memory of the primary insomnia group was significantly worse than that of the healthy controls group, whereas there was no significant difference in long-term delayed recognition between the two groups. The naming and language scores of the primary insomnia group were significantly lower than those of the healthy controls group. The total Pittsburgh Sleep Quality Index score was positively correlated with anxiety and depression symptoms.
This study emphasized the correlation between emotional symptoms and cognitive dysfunction in patients with primary insomnia. Simultaneously, their levels of anxiety and depression were both positively correlated with the degree of cognitive dysfunction.
原发性失眠是一种常见且复杂的疾病，其特征是一系列严重程度各异的症状及后果。长期睡眠障碍可导致焦虑、抑郁和认知功能障碍。本研究旨在调查原发性失眠患者情绪变化与认知功能障碍之间的关系，并探索影响该疾病的因素。
研究参与者包括40例根据《国际睡眠障碍分类第3版》诊断的原发性失眠患者以及来自温州市第七人民医院的48名健康对照者。采用匹兹堡睡眠质量指数、蒙特利尔认知评估量表、汉密尔顿焦虑量表和汉密尔顿抑郁量表评估临床症状。使用t检验、卡方检验、Pearson相关性分析和网络分析来检验原发性失眠参与者情绪症状与认知功能之间的相互关系。
原发性失眠组的即时记忆和延迟记忆均显著差于健康对照组，而两组之间的长期延迟识别无显著差异。原发性失眠组的命名和语言得分显著低于健康对照组。匹兹堡睡眠质量指数总分与焦虑和抑郁症状呈正相关。
本研究强调了原发性失眠患者情绪症状与认知功能障碍之间的相关性。同时，他们的焦虑和抑郁水平均与认知功能障碍程度呈正相关。
