超声造影（CEUS）对胆囊疾病评估的诊断性能1。
Diagnostic performance of contrast-enhanced ultrasound (CEUS) for the evaluation of gallbladder diseases1.
作者信息
Negrão de Figueiredo G, Mueller-Peltzer K, Zengel P, Armbruster M, Rübenthaler J, Clevert D A
机构信息
Department of Radiology, Interdisciplinary Ultrasound-Center Ludwig-Maximilians- University of Munich - Grosshadern Campus, Marchioninistr, Munich, Germany.
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität München, Munich, Germany.
出版信息
Clin Hemorheol Microcirc. 2018;69(1-2):83-91. doi: 10.3233/CH-189116.
BACKGROUND
Contrast-enhanced ultrasound (CEUS) has been used as an additional imaging technique to conventional ultrasound in order to clarify gallbladder findings, CEUS is easy and fast to perform, overcomes the limitations of gray-scale ultrasonography and is a safe tool.
OBJECTIVE
The aim of this retrospective mono-center analysis study is to evaluate the diagnostic performance of CEUS in the assessment of gallbladder disease by comparing its results with additional CT findings.
METHODS
A total of 24 patients between 2009 and 2017 with unclear gallbladder appearance were retrospectively analysed. The contrast agent administered was a second-generation blood pool agent (SonoVue®, Bracco, Milan, Italy). Examinations were performed and interpreted by a single experienced radiologist with more than fifteen years' experience.
RESULTS
24 patients were successfully examined without any adverse reaction. CEUS presented a sensitivity of 75%, a specificity of 100.0%, a positive predictive value of 100.0% and a negative predictive value of 95%.
CONCLUSIONS
In conclusion, the excellent results in this study acknowledged that CEUS is a feasible alternative tool to differentiate gallbladder pathologic alterations.
背景
超声造影（CEUS）已被用作传统超声的一种辅助成像技术，以明确胆囊检查结果。CEUS操作简便、快速，克服了灰阶超声检查的局限性，是一种安全的工具。
目的
这项回顾性单中心分析研究的目的是通过将CEUS的结果与其他CT检查结果进行比较，评估CEUS在胆囊疾病评估中的诊断性能。
方法
回顾性分析了2009年至2017年间24例胆囊外观不明确的患者。使用的造影剂是第二代血池造影剂（声诺维®，意大利米兰百胜公司）。检查由一位经验丰富的、有超过15年经验的放射科医生进行并解读。
结果
24例患者均成功完成检查，未出现任何不良反应。CEUS的敏感性为75%，特异性为100.0%，阳性预测值为100.0%，阴性预测值为95%。
结论
总之，本研究的良好结果表明，CEUS是鉴别胆囊病理改变的一种可行的替代工具。
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