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长期暴露于环境空气污染物与心理健康状况:一项全国范围内基于人群的横断面研究。

Long-term exposure to ambient air pollutants and mental health status: A nationwide population-based cross-sectional study.

机构信息

Department of Family Medicine, Research Institute of Medical Science, Konkuk University School of Medicine, Konkuk University Medical Center, Seoul, South Korea.

Department of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.

出版信息

PLoS One. 2018 Apr 9;13(4):e0195607. doi: 10.1371/journal.pone.0195607. eCollection 2018.

Abstract

There is a suspected but unproven association between long-term exposure to ambient air pollution and mental health. The aim of this study is to investigate the association between long-term exposure to ambient air pollution and subjective stress, depressive disorders, health-related quality of life (QoL) and suicide. We selected 124,205 adults from the Korean Community Health Survey in 2013 who were at least 19 years old and who had lived in their current domiciles for > five years. Based on the computer-assisted personal interviews to measure subjective stress in daily life, EuroQoL-5 dimensions, depression diagnosis by a doctor, suicidal ideation, and suicidal attempts, we evaluated the risk of mental disorders using multiple logistic regression analysis according to the quartiles of air pollutants, such as particulate matter <10μm (PM10), nitrogen dioxide (NO2), carbon monoxide (CO), and sulfur dioxide, using yearly average concentration between August 2012 and July 2013. The prevalence of high stress, poor QoL, depressiveness, diagnosis of depression, and suicide ideation was positively associated with high concentrations of PM10, NO2, and CO after adjusting for confounding factors. Men were at increased risk of stress, poor QoL, and depressiveness from air pollution exposure than were women. The risk of higher stress or poor QoL in subjects < age 65 increased with air pollution more than did that in subjects ≥ age 65. Long-term exposure to ambient air pollution may be an independent risk factor for mental health disorders ranging from subjective stress to suicide ideation.

摘要

长期暴露于环境空气污染与心理健康之间存在可疑但未经证实的关联。本研究旨在调查长期暴露于环境空气污染与主观压力、抑郁障碍、健康相关生活质量(QoL)和自杀之间的关联。我们从 2013 年韩国社区健康调查中选择了 124205 名至少 19 岁且在当前住所居住> 5 年的成年人。根据计算机辅助的个人访谈来衡量日常生活中的主观压力、欧洲五维健康量表、医生诊断的抑郁、自杀意念和自杀企图,我们根据空气污染(如 PM10、二氧化氮、一氧化碳和二氧化硫)的四分位数使用多变量逻辑回归分析评估了精神障碍的风险,使用 2012 年 8 月至 2013 年 7 月之间的年平均浓度。在调整混杂因素后,高压力、低生活质量、抑郁、抑郁诊断和自杀意念的患病率与 PM10、NO2 和 CO 浓度升高呈正相关。与女性相比,男性暴露于空气污染与压力、低生活质量和抑郁的风险增加。与≥ 65 岁的受试者相比,< 65 岁的受试者中,较高的压力或低生活质量的风险随着空气污染的增加而增加。长期暴露于环境空气污染可能是从主观压力到自杀意念等心理健康障碍的独立危险因素。

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