College of Animal Science, Southwest University, Chongqing 402460, China; Department of Biological Sciences, National University of Singapore, 117543, Singapore.
Department of Biological Sciences, National University of Singapore, 117543, Singapore.
Fish Shellfish Immunol. 2018 Jun;77:319-327. doi: 10.1016/j.fsi.2018.03.046. Epub 2018 Apr 6.
With the development of intensive aquaculture, economic losses increasingly result from fish mortality due to pathogen infection. In recent years, a growing number of researchers have used transcriptomic and proteomic analyses to study fish immune responses to exogenous pathogen infection. Integrating transcriptomic and proteomic analyses provides a better understanding of the fish immune system including gene expression, regulation, and the intricate biological processes underlying immune responses against infection. This review focuses on the recent advances in the fields of transcriptomics and proteomics, which have contributed to our understanding of fish immunity to exogenous pathogens.
随着集约化水产养殖的发展，由于病原体感染导致鱼类死亡造成的经济损失日益增加。近年来，越来越多的研究人员利用转录组学和蛋白质组学分析来研究鱼类对外源病原体感染的免疫反应。整合转录组学和蛋白质组学分析可以更好地了解鱼类免疫系统，包括基因表达、调控以及免疫反应对抗感染的复杂生物学过程。本综述重点介绍了转录组学和蛋白质组学领域的最新进展，这些进展有助于我们了解鱼类对外源病原体的免疫。
