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前路手术治疗下颈椎骨折脱位伴脊髓损伤:5至15年随访

Surgical Treatment of Lower Cervical Fracture-Dislocation with Spinal Cord Injuries by Anterior Approach: 5- to 15-Year Follow-Up.

作者信息

Gao Wenjie, Wang Biao, Hao Dingjun, Zhu Ziqi, Guo Hua, Li Hui, Kong Lingbo

机构信息

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shanxi, China.

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shanxi, China.

出版信息

World Neurosurg. 2018 Jul;115:e137-e145. doi: 10.1016/j.wneu.2018.03.213. Epub 2018 Apr 6.

Abstract

BACKGROUND

Lower cervical fracture-dislocations frequently occur with spinal cord injuries. There is no clear consensus on best treatment option. Anterior approach surgery with direct decompression and reduction has become widely accepted. We assessed clinical outcomes of anterior approach surgery in a retrospective cohort study.

METHODS

From January 2001 to January 2011, 312 patients with lower cervical spine fracture-dislocation with spinal cord injuries who were treated by the anterior approach were retrospectively analyzed. Of 312 patients, 218 (70%; 121 men and 97 women) met inclusion criteria. Clinical efficacy was evaluated using Odom's criteria and statistical analysis based on Cobb angle of kyphosis and Neck Disability Index and Japanese Orthopedic Association scores. Neurofunctional recovery of patients was assessed by the American Spinal Injury Association system.

RESULTS

Average follow-up was 8.9 ± 2.9 years (range, 5-15 years). Kyphosis angle and Neck Disability Index and Japanese Orthopaedic Association scores were significantly changed from preoperative values of 10.6° ± 8.9° and 39.7 ± 4.3 and 7.6 ± 2.4 to last follow-up values of -5.2° ± 8.6° and 10.8 ± 4.6 and 15.6 ± 1.2 (P < 0.05). Of patients, 197 (90.4%) had good to excellent outcomes, 14 (6.4%) had satisfactory outcomes, and 7 (3.2%) had poor outcomes. Varying degrees of neurologic function recovery were shown by 143 of the original 218 patients (65.6%) and 140 of 191 patients with incomplete paralysis (73.3%).

CONCLUSIONS

For lower cervical fracture-dislocation with spinal cord injuries, satisfactory clinical outcomes can be obtained with an anterior approach. The anterior approach restored normal cervical spine structure and promoted functional recovery to achieve a good long-term curative effect.

摘要

背景

下颈椎骨折脱位常伴有脊髓损伤。对于最佳治疗方案尚无明确共识。前路手术直接减压和复位已被广泛接受。我们在一项回顾性队列研究中评估了前路手术的临床疗效。

方法

回顾性分析2001年1月至2011年1月采用前路手术治疗的312例下颈椎骨折脱位伴脊髓损伤患者。312例患者中,218例(70%;男性121例,女性97例)符合纳入标准。采用奥多姆标准评估临床疗效,并基于后凸Cobb角、颈部残疾指数和日本矫形外科学会评分进行统计分析。采用美国脊髓损伤协会系统评估患者的神经功能恢复情况。

结果

平均随访时间为8.9±2.9年(范围5 - 15年)。后凸角、颈部残疾指数和日本矫形外科学会评分从术前的10.6°±8.9°、39.7±4.3和7.6±2.4显著变化至末次随访时的-5.2°±8.6°、10.8±4.6和15.6±1.2(P < 0.05)。患者中,197例(90.4%)疗效为优至良,14例(6.4%)疗效满意,7例(3.2%)疗效差。最初218例患者中有143例(65.6%)以及191例不完全瘫痪患者中有140例(73.3%)显示出不同程度的神经功能恢复。

结论

对于下颈椎骨折脱位伴脊髓损伤,前路手术可获得满意的临床疗效。前路手术恢复了颈椎的正常结构,促进了功能恢复,取得了良好的长期疗效。

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