Medical College, Aga Khan University Hospital, Karachi, Pakistan.
Section of Ophthalmology, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Can J Ophthalmol. 2018 Apr;53(2):94-97. doi: 10.1016/j.jcjo.2017.07.027. Epub 2018 Mar 9.
To report the incidence of endophthalmitis after the use of intravitreal injection for anti-vascular endothelial growth factor therapy.
This was a single-centre retrospective study conducted at the Aga Khan University Hospital, Pakistan. A total of 11 128 injections were administered to 2054 patients between January 2013 and December 2015. All procedures were performed in an operating room setting, and postinjection antibiotics were prescribed.
Three cases of endophthalmitis occurred during the study period, with the per-injection risk of endophthalmitis being 0.027%.
The results highlight the benefit of administering intravitreal injections in a surgical setting in addition to enforcing quality protocols. We also recommend further investigation to scrutinize the role of antibiotics prescribed after deploying intravitreal injections so that unnecessary use of such may be curtailed.
报告抗血管内皮生长因子治疗玻璃体腔内注射后眼内炎的发生率。
这是一项在巴基斯坦 Aga Khan 大学医院进行的单中心回顾性研究。2013 年 1 月至 2015 年 12 月，共有 2054 名患者接受了 11128 次注射。所有操作均在手术室环境中进行，并在注射后开具抗生素。
研究期间发生了 3 例眼内炎，每次注射的眼内炎风险为 0.027%。
研究结果突出了在手术环境中进行玻璃体腔内注射的益处，同时还强调了要执行质量协议。我们还建议进一步研究，以仔细检查注射后开具的抗生素的作用，从而减少不必要的抗生素使用。
