Libanore M, Bicocchi R, Raise E, Sighinolfi L, Bedetti A, Montanari P, Fagioli F, Benini A, Schiattone M L, Ghinelli F
Regione Emilia-Romagna U.S.L. n. 31-Arcispedale S. Anna-Ferrara.
Minerva Med. 1987 Dec 31;78(24):1805-12.
Serum zinc levels were assayed in patients with AIDS and related syndromes, using spectrophotometry and atomic absorption. Statistical data have shown that serum zinc levels, in addition to being significantly lower (p less than 0.001) among different groups and controls, decrease progressively with the worsening of the clinical and immunological picture from LAS to AIDS. Serum zinc levels in patients with AIDS and ARC have, moreover, been demonstrated to be related (r = 0.8240; p less than 0.001) to the lymphocyte subset CD4 helper-induced. These results suggest that serum zinc determination and possibly zinc therapy might be reasonably considered in the management of patients with symptoms of HIV infection.
采用分光光度法和原子吸收法对艾滋病患者及相关综合征患者的血清锌水平进行了测定。统计数据表明，血清锌水平不仅在不同组和对照组中显著降低（p<0.001），而且随着临床和免疫状况从淋巴结病相关综合征（LAS）到艾滋病的恶化而逐渐下降。此外，艾滋病患者和艾滋病相关综合征（ARC）患者的血清锌水平已被证明与淋巴细胞亚群CD4辅助诱导相关（r = 0.8240；p<0.001）。这些结果表明，在管理有HIV感染症状的患者时，合理考虑测定血清锌水平并可能进行锌治疗。
