Kreydin Evgeniy I, Chyu Jennifer, Lerner Lori
Institute of Urology, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.
David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Int J Urol. 2018 Jun;25(6):549-553. doi: 10.1111/iju.13560. Epub 2018 Apr 6.
To compare characteristics and outcomes of benign prostatic hyperplasia patients undergoing prostate laser ablation with those undergoing laser enucleation using a nationwide cohort.
Men who underwent prostate laser ablation (n=10054) or laser enucleation (n=1705) between 2011 and 2015 were identified by the common procedural terminology code as recorded in the National Surgical Quality Improvement Program database. Preoperative, intraoperative and postoperative parameters were compared between the groups using univariate and multivariate analysis.
Prostate laser ablation patients were older, had more comorbidities and were more likely to have abnormal laboratory values. Enucleations were significantly longer and more likely to result in a hospital stay >1day. Enucleation patients were also more likely to require a blood transfusion postoperatively, but less likely to experience urinary tract infection and sepsis on both univariate and multivariate analysis adjusted for preoperative and intraoperative factors.
Although laser enucleation and prostate laser ablation are both considered minimally invasive techniques, significant differences in patient selection, intraoperative factors and postoperative complications are identified in this national cohort. The present study shows that despite similar outcomes in prospective single-center studies, prostate laser ablation and laser enucleation have distinct practice patterns in a broader national context.
利用全国性队列比较接受前列腺激光消融术的良性前列腺增生患者与接受激光剜除术的患者的特征和结局。
通过国家外科质量改进计划数据库中记录的通用手术术语代码,确定2011年至2015年间接受前列腺激光消融术(n = 10054)或激光剜除术(n = 1705)的男性。使用单因素和多因素分析比较两组患者的术前、术中和术后参数。
前列腺激光消融术患者年龄更大,合并症更多,实验室检查值异常的可能性更高。剜除术时间明显更长,且更有可能导致住院时间>1天。在对术前和术中因素进行调整的单因素和多因素分析中,剜除术患者术后也更有可能需要输血,但发生尿路感染和脓毒症的可能性较小。
尽管激光剜除术和前列腺激光消融术均被视为微创技术,但在这个全国性队列中,患者选择、术中因素和术后并发症方面存在显著差异。本研究表明,尽管在前瞻性单中心研究中结局相似,但在更广泛的全国范围内,前列腺激光消融术和激光剜除术具有不同的实践模式。