Department of Rheumatology, AP-HP, CHU Henri Mondor, Créteil, France.
Université Paris Est Créteil, EA 7379 - EpidermE, Créteil, France.
J Eur Acad Dermatol Venereol. 2018 Oct;32(10):1702-1709. doi: 10.1111/jdv.14986. Epub 2018 May 9.
The physical, social and mental burden of psoriasis is well known, but its occupational impact has been less investigated.
To assess the impact of psoriasis on the working life of patients compared with the general population.
A national survey compared people with and without psoriasis using online questionnaires. In addition to the demographic, medical and professional characteristics, data on recent absenteeism and presenteeism were captured using the validated WPAI-PSO questionnaire.
The patient sample comprised 714 with psoriasis (PsO), including 81 treated with systemic therapies (PsoST), and 84 with associated psoriatic arthritis (PsO + PsA). The control sample comprised 604 active subjects representative of the French population. Compared to controls, the impact of the disease on working life was no greater in PsO patients. Conversely, unemployment within the past 5 years and mean number of sick leaves within the previous year were more frequent in PsO + PsA. In patients with active psoriasis skin lesions, all aspects of the WPAI questionnaire were negatively impacted in PsoST and PsO + PsA patients, but not in PsO patients: Levels of absenteeism were 3.3% in controls, 5.6% in PsO (NS), 8.3% in PsoST (P < 0.05) and 13.0% in Ps0 + PsA (P < 0.05); impairment in presenteeism reached 27.0%, 21.2% (NS), 43.5% (P < 0.05) and 53.2% (P < 0.05), respectively, while overall work impairment was 27.9%, 22.2% (NS), 46.3% (P < 0.05) and 57.6% (P < 0.05), respectively. Nevertheless, a higher proportion of PsoST and PsO + PsA patients reported that work was more important than any other activity in their life.
The occupational impact of psoriasis is important and significant in patients who receive systemic therapy or have concurrent PsA but minimal or absent in other psoriasis patients. The findings show that psoriasis patients have a high level of motivation to work.
银屑病的身体、社会和心理负担众所周知，但对其职业影响的研究较少。
评估银屑病对患者工作生活的影响与普通人群相比。
一项全国性调查使用在线问卷比较了银屑病患者和非银屑病患者。除了人口统计学、医学和职业特征外，还使用经过验证的 WPAI-PSO 问卷捕获了最近缺勤和在职病假的数据。
患者样本包括 714 名银屑病患者（PsO），其中 81 名接受系统治疗（PsoST），84 名患有相关的银屑病关节炎（PsO+PsA）。对照组包括 604 名具有代表性的法国人群中的活跃受试者。与对照组相比，在过去 5 年内，银屑病患者的工作生活受疾病影响没有更大。相反，在过去 5 年内失业和过去 1 年内平均请病假的人数在 PsO+PsA 中更为常见。在患有活动性银屑病皮肤病变的患者中，WPAI 问卷的所有方面在 PsoST 和 PsO+PsA 患者中都受到负面影响，但在 PsO 患者中没有：对照组的缺勤率为 3.3%，PsO 为 5.6%（无统计学意义），PsoST 为 8.3%（P<0.05），Ps0+PsA 为 13.0%（P<0.05）；在职病假的损伤程度分别为 27.0%、21.2%（无统计学意义）、43.5%（P<0.05）和 53.2%（P<0.05），而整体工作损伤程度分别为 27.9%、22.2%（无统计学意义）、46.3%（P<0.05）和 57.6%（P<0.05）。然而，更高比例的 PsoST 和 PsO+PsA 患者报告说工作比他们生活中的任何其他活动都更重要。
在接受系统治疗或同时患有 PsA 的患者中，银屑病的职业影响很重要且显著，但在其他银屑病患者中则微不足道或不存在。研究结果表明，银屑病患者有很高的工作动力。
