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一项针对三级医疗机构的队列研究表明,慢性鼻窦炎患者在内镜鼻窦手术中部分切除中鼻甲不会导致空鼻综合征风险增加。

Partial resection of the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis does not lead to an increased risk of empty nose syndrome: a cohort study of a tertiary practice.

作者信息

Tan Neil C-W, Goggin Rachel, Psaltis Alkis J, Wormald Peter-John

机构信息

Department of Surgery-Otolaryngology, University of Adelaide, Adelaide, Australia.

出版信息

Int Forum Allergy Rhinol. 2018 Apr 6. doi: 10.1002/alr.22127.

DOI:10.1002/alr.22127
PMID:29633570
Abstract

BACKGROUND

The treatment of the middle turbinate (MT) during endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) remains a contentious issue with arguments both for and against its resection. The purpose of this study was to examine the clinical impact of partial MT resection (PMTR) during ESS, paying particular attention to the risk of developing empty nose syndrome (ENS) and alteration to olfaction.

METHODS

This cohort study was performed on prospectively collected data. A total of 177 patients underwent ESS for CRS; 93 had PMTR and 84 MT preservation (MTP). Preoperative data collection included subjective symptom scores as per the Adelaide Disease Severity Score (ADSS), Lund-Mackay scores, and nasal polyp status. The Empty Nose Syndrome 6-Item Questionnaire (ENS6Q) was administered by telephone consultation and analyzed alongside postoperative symptom scores.

RESULTS

There was no difference in ENS6Q scores in patients who underwent PMTR vs those who had MTP. Patients who underwent PMTR had a higher baseline disease on Lund-Mackay scoring, and were more likely to be nasal polyp patients and be undergoing revision surgery. ADSS scores demonstrated significant improvements in all rhinologic symptoms, with no difference between the cohorts.

CONCLUSION

PMTR is an adjunctive procedure to ESS. This study has established that PMTR as performed by the senior author carries no additional risk of developing ENS symptoms as defined by the ENS6Q, and that it carries no additional risk to olfaction or other rhinologic symptoms. PMTR can be safely considered at time of ESS, especially in patients at risk of lateralization of the MT.

摘要

背景

在慢性鼻-鼻窦炎(CRS)的鼻内镜鼻窦手术(ESS)中,中鼻甲(MT)的处理仍然是一个有争议的问题,对于是否切除存在不同观点。本研究的目的是探讨ESS期间部分中鼻甲切除术(PMTR)的临床影响,特别关注空鼻综合征(ENS)发生风险以及嗅觉改变情况。

方法

本队列研究基于前瞻性收集的数据进行。共有177例因CRS接受ESS的患者,其中93例行PMTR,84例保留中鼻甲(MTP)。术前数据收集包括根据阿德莱德疾病严重程度评分(ADSS)的主观症状评分、Lund-Mackay评分及鼻息肉状态。通过电话咨询进行空鼻综合征6项问卷(ENS6Q)调查,并与术后症状评分一起分析。

结果

接受PMTR的患者与接受MTP的患者在ENS6Q评分上无差异。接受PMTR的患者在Lund-Mackay评分上基线疾病更严重,更可能是鼻息肉患者且正在接受翻修手术。ADSS评分显示所有鼻科症状均有显著改善,两组之间无差异。

结论

PMTR是ESS的辅助手术。本研究表明,第一作者所施行的PMTR不会增加ENS6Q所定义的ENS症状发生风险,也不会增加嗅觉或其他鼻科症状的风险。在ESS时可安全考虑PMTR,尤其是对于有中鼻甲外移风险的患者。

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