Chomette G, Vaillant J M, Auriol M
Service d'Anatomie pathologique, Hôpital de la Pitié, Paris.
Rev Stomatol Chir Maxillofac. 1987;88(5):350-5.
One case of mesenchymal chondrosarcoma of the mandible is reported in a 18 years-old man. The patient noted swelling and pain and roentgenography showed an osteolytic lesion of the right mandible. Histologically, the feature was obvious with chondroid sheets of round ovoid or elongated cells. Immunohistochemically, numerous cells had positive S-100 protein and vimentin. The electron microscopy showed numerous undifferentiated cells and also fibroblastic and cartilaginous cells. The prognosis of this tumor, usually bad, cannot be yet appreciated in this case (follow-up of only 3 months). The histogenesis of this peculiar variety of chondrosarcoma is discussed.
本文报道了1例18岁男性下颌骨间叶性软骨肉瘤。患者自觉肿胀及疼痛，X线检查显示右下颌骨有溶骨性病变。组织学检查可见明显特征，即由圆形、卵圆形或梭形细胞构成的软骨样片。免疫组化检查显示，大量细胞S-100蛋白和波形蛋白呈阳性。电镜检查可见大量未分化细胞，还有成纤维细胞和软骨细胞。该肿瘤预后通常较差，但此例患者（仅随访3个月）目前尚无法评估预后。文中还讨论了这种特殊类型软骨肉瘤的组织发生。
