Gao F X
Zhonghua Zhong Liu Za Zhi. 1985 Sep;7(5):354-6.
This paper reports 4 cases of mesenchymal chondrosarcoma, 1 case in the retroperitoneum, 1 the left mandible, 1 right thoracic wall and 1 right thigh. 2 males and 2 females. The age ranged from 18 to 42 with an average of 29 years. In this series, 3 patients are still alive after operation and one died one year postoperatively. Microscopic examination: the tumor was made up not only of undifferentiated mesenchymal cells, but also of well-differentiated cartilaginous islands and hemangiopericytomalike lesions. Transitions between the undifferentiated small cells and neighbouring chondrocytes or chondroid matrix and collagenous fibers can be found microscopically in all cases. The authors emphasize that collagenous fibers between the undifferentiated cells play an important role in the formation of cartilaginous islands. The differential diagnosis of this disease is discussed.
本文报告了4例间叶性软骨肉瘤，1例位于腹膜后，1例在左下颌骨，1例在右胸壁，1例在右大腿。2例男性，2例女性。年龄范围为18至42岁，平均29岁。在这组病例中，3例患者术后仍存活，1例术后1年死亡。显微镜检查：肿瘤不仅由未分化的间叶细胞组成，还由分化良好的软骨岛和血管外皮细胞瘤样病变组成。在所有病例中，显微镜下均可发现未分化的小细胞与相邻软骨细胞或软骨样基质及胶原纤维之间的过渡。作者强调未分化细胞之间的胶原纤维在软骨岛的形成中起重要作用。并对该疾病的鉴别诊断进行了讨论。
