Abdullah Ali S, Adel Ahmad M, Hussein Radwa M, Abdullah Mohammed Aj, Yousaf Anil, Mudawi Deena, Mohamed Shehab F, Nashwan Abdulqadir J, Soliman Dina, Ibrahim Feryal, Yassin Mohamed A
Resident, Internal Medicine, Hamad Medical Corporation (HMC), Doha, Qatar.
Pharmacists, Department of Pharmacy, NCCCR, Hamad Medical Corporation (HMC), Doha, Qatar.
Acta Biomed. 2018 Apr 3;89(3-S):23-27. doi: 10.23750/abm.v89i3-S.7216.
We report a rare case of hypercalcemia and acute pancreatitis in a subject with acute promyelocytic leukemia (APL) and pulmonary tuberculosis, during all-trans-retinoic acid (ATRA) treatment. Both associated complications were potentially due to several causes. A careful monitoring and exclusion of all causative factors must be addressed. Further research is necessary to improve our understanding of risk factors for these complications in patients with (APL). Studying these patterns may help us to improve outcomes for all children and young adults with hematologic malignancies.
我们报告了1例急性早幼粒细胞白血病(APL)合并肺结核的患者在全反式维甲酸(ATRA)治疗期间出现高钙血症和急性胰腺炎的罕见病例。这两种相关并发症可能由多种原因引起。必须对所有致病因素进行仔细监测和排除。有必要进行进一步研究,以加深我们对APL患者这些并发症危险因素的理解。研究这些模式可能有助于我们改善所有血液系统恶性肿瘤儿童和年轻成人的治疗结果。