Department of Ophthalmology, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Department of Ophthalmology, Lady Cilento Children's Hospital, Brisbane, Australia.
Asia Pac J Ophthalmol (Phila). 2018 Sep-Oct;7(5):356-363. doi: 10.22608/APO.2017151. Epub 2018 Apr 10.
The recent International Society for the Study of Vascular Anomalies (ISSVA) classification of vascular anomalies can be applied to orbital lesions, dividing them into vascular tumors and vascular malformations. Orbital cavernous hemangiomas are probably best considered cavernous venous malformations under this classification. Management of symptomatic lesions can be with surgical excision or stereotactic fractionated radiotherapy in selected cases. Beta-blockers including propranolol and topical timolol maleate represent first-line therapy for infantile hemangiomas, although surgery has a role in selected cases. Orbital venous-lymphatic malformations are problematic but with improved imaging, neuroradiological intervention, and a multidisciplinary approach to management, outcomes are improving.
最近的国际脉管性疾病研究学会（ISSVA）血管异常分类可应用于眼眶病变，将其分为血管肿瘤和血管畸形。根据该分类，眼眶海绵状血管瘤可能最好被视为海绵状静脉畸形。有症状的病变可选择手术切除或立体定向分次放射治疗。β受体阻滞剂，包括普萘洛尔和马来酸噻吗洛尔滴眼液，是婴幼儿血管瘤的一线治疗药物，尽管手术在某些情况下也有作用。眼眶静脉淋巴管畸形是一个棘手的问题，但随着影像学技术的提高、神经放射介入技术的发展，以及多学科管理方法的应用，其治疗效果正在不断改善。
