Ruffmann K, Kücherer H, Mandelbaum A, Kübler W
Department of Internal Medicine (Cardiology) Heidelberg University, F.R.G.
Z Kardiol. 1987;76 Suppl 3:78-81.
In order to study the influence of various kinds of left ventricular hypertrophy on left ventricular filling pattern, 20 patients (five dilated cardiomyopathy, five hypertension, five end-stage renal disease, five hypertrophic cardiomyopathy), and five normals were studied by M-mode and pulsed 2D-Doppler echocardiography. Left ventricular dimensions, volumes and mass were derived from standard M-mode echocardiograms. Doppler velocity measurements of mitral inflow provided calculation of left ventricular diastolic filling parameters. While left ventricular diastolic function bore no relation to the impairment of left ventricular systolic function, there was a statistically significant correlation of left ventricular mass/volume ratio and impairment of left ventricular diastolic function. In patients with hypertrophic cardiomyopathy, the parameters varied widely, and additional factors seem to determine left ventricular diastolic function in this group.
为研究各种类型的左心室肥厚对左心室充盈模式的影响，我们采用M型和脉冲二维多普勒超声心动图对20例患者（5例扩张型心肌病、5例高血压、5例终末期肾病、5例肥厚型心肌病）及5例正常人进行了研究。左心室尺寸、容积和质量由标准M型超声心动图得出。二尖瓣血流的多普勒速度测量用于计算左心室舒张期充盈参数。虽然左心室舒张功能与左心室收缩功能损害无关，但左心室质量/容积比与左心室舒张功能损害之间存在统计学上的显著相关性。在肥厚型心肌病患者中，参数变化很大，似乎还有其他因素决定该组患者的左心室舒张功能。
