在比较 3 种商业饮料的随机试验中，无论体重还是性别都不会影响饮料水合指数的结果。

Neither body mass nor sex influences beverage hydration index outcomes during randomized trial when comparing 3 commercial beverages.

机构信息

Department of Kinesiology, Sonoma State University, Rohnert Park, CA.

Department of Radiation Oncology, University of Florida Health Cancer Center, Cancer and Genetics Research, Gainesville, FL.

出版信息

Am J Clin Nutr. 2018 Apr 1;107(4):544-549. doi: 10.1093/ajcn/nqy005.

DOI:10.1093/ajcn/nqy005

PMID:29635499

Abstract

BACKGROUND

The beverage hydration index (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric, and the impact of body mass, sex, and reproducibility has yet to be investigated.

OBJECTIVES

To assess the independent impact of body mass and sex on BHI using beverages not previously assessed, including an amino acid-based oral rehydration solution (AA-ORS), a glucose-containing ORS (G-ORS), and a sports drink (SpD), compared with water (control). The reproducibility of the results was examined using statistical modeling (bootstrap analysis).

DESIGN

Using a repeated-measures design, 40 euhydrated and fasted subjects (17 male, 23 female; urine specific gravity <1.025) were studied on 4 separate occasions. During each trial, subjects ingested 1 L of each beverage, and urine output was measured immediately postingestion and at 1-h intervals for the next 4 h. The BHI was calculated as a ratio of each individual's cumulative urine output after drinking 1 L of water over their cumulative urine output after drinking each of the test beverages.

RESULTS

The calculated mean ± SD BHIs of the beverages were as follows: water (1.0 ± 0.0), AA-ORS (1.15 ± 0.28), G-ORS (1.21 ± 0.28), and SpD (1.09 ± 0.26). The BHI for both AA-ORS and G-ORS was greater than that for water (P < 0.05). Despite overall differences in body mass, neither body mass nor sex independently affected BHI. Based upon statistical modeling, our results demonstrate excellent reproducibility of outcomes and external validity.

CONCLUSIONS

Our results suggest that the BHI may be used and interpreted with confidence independently of body mass or sex. Furthermore, a novel carbohydrate-free AA-ORS and a traditional commercially available G-ORS were superior to water in optimizing hydration, whereas SpD was not. This trial was registered at clinicaltrials.gov as NCT03262597.

摘要

背景

饮料水合指数（BHI）评估任何消耗性液体相对于水的水合潜力。BHI 是一个相对较新的指标，其对体重、性别和重现性的影响尚未得到研究。

目的

使用以前未评估过的饮料，包括一种基于氨基酸的口服补液溶液（AA-ORS）、一种含葡萄糖的口服补液溶液（G-ORS）和一种运动饮料（SpD），与水（对照）相比，评估体重和性别对 BHI 的独立影响。使用统计建模（自举分析）检查结果的重现性。

设计

使用重复测量设计，40 名水合状态正常且空腹的受试者（17 名男性，23 名女性；尿比重<1.025）在 4 个不同时间点进行了研究。在每次试验中，受试者摄入 1 L 每种饮料，立即在摄入后测量尿排出量，并在接下来的 4 小时内每 1 小时测量一次。BHI 计算为个体在饮用 1 L 水后的累积尿量与饮用每种测试饮料后的累积尿量之比。

结果

计算得出的饮料平均±标准差 BHI 如下：水（1.0±0.0）、AA-ORS（1.15±0.28）、G-ORS（1.21±0.28）和 SpD（1.09±0.26）。AA-ORS 和 G-ORS 的 BHI 均大于水（P<0.05）。尽管体重存在总体差异，但体重或性别均不能独立影响 BHI。基于统计建模，我们的结果表明结果具有极好的重现性和外部有效性。