Nutrabolt Applied and Molecular Sciences Laboratory, Auburn University, School of Kinesiology, Auburn, AL, USA.
Nutrabolt, Austin, TX, USA.
J Int Soc Sports Nutr. 2024 Dec;21(1):2296888. doi: 10.1080/15502783.2023.2296888. Epub 2023 Dec 22.
The purpose of this study was to examine the acute effects of a multi-ingredient, low calorie dietary supplement (MIDS, XTEND® Healthy Hydration) on 5-kilometer (5-km) time trial performance and blood electrolyte concentrations compared to a carbohydrate-electrolyte beverage (CE, GATORADE® Thirst Quencher) and distilled water (W).
During visit 1 (V1), participants (10 men and 10 women, 20-35 years old, BMI ≤ 29 kg/m, recreationally active) reported to the laboratory whereby the following tests were performed: i) height and weight measurements, ii) body composition analysis, iii) treadmill testing to measure maximal aerobic capacity, and iv) 5-km time trial familiarization. The second visit (V2) was one week after V1 in the morning (0600 - 0900) and participants arrived 12-14 h fasted (no food or drink). The first battery of assessments (V2-T1) included nude body mass, urine specific gravity (USG), a profile of mood states (POMS) questionnaire, and the completion of a visual analogue scale (VAS) questionnaire to quantify cramping. Then heart rate (HR), blood pressure (BP), total body hydration (via bioelectrical impedance spectroscopy [BIS]) were examined. Finally, a measurement of blood markers via finger stick was performed. Participants consumed a randomized beverage (16 fl. oz. of MIDS, 16 fl. oz. of W, or 16 fl. oz. of CE) within 3 min followed by a 45-min rest. Following the rest period, a second battery (V2-T2) was performed whereby participants' USG was assessed and they completed the POMS and VAS questionnaires, and HR, BP, and blood markers were measured. The participants then performed a 5-km treadmill time trial. Immediately following the 5-km time trial, participants completed a third testing battery (V2-T3) that began with blood markers, HR and BP assessments, followed by nude body weight assessment, and the POMS and VAS questionnaires. After 60 min, a fourth battery (V2-T4) was performed that included HR, BP, and blood markers. After sitting quietly for another 60 min a fifth battery assessment was performed (V2-T5) that included participants' USG, POMS and VAS questionnaires, HR, BP, blood markers, and total body hydration. Visits 3 (V3) and 4 (V4) followed the same protocol except a different randomized drink (16 oz. of CE, MIDS, or W) was consumed; all of which were separated by approximately one week.
No differences occurred between conditions for 5-km time trial completion, indirect calorimetry outcomes during 5-km time trials, USG, or nude mass measurements ( > 0.05 for all relevant statistical tests). However, blood potassium and the sodium/potassium ratio displayed significant interactions ( < 0.05), and post hoc testing indicated these values were better maintained in the MIDS versus other conditions. Post-exercise cramp prevalence was greater in the CE ( < 0.05) and trended higher with W ( = 0.083) compared to the MIDS condition. Post-exercise cramp severity was also elevated with the W and CE beverages ( < 0.05) but not the MIDS ( = 0.211).
The MIDS did not affect 5-km time trial performance but exhibited favorable effects on blood electrolyte and post-exercise self-reporting cramp outcomes compared to the CE and W drinks.
本研究旨在比较一种多成分、低热量膳食补充剂(MIDS,XTEND®健康补水)与碳水化合物-电解质饮料(CE,GATORADE®口渴终结者)和蒸馏水(W)对 5 公里(5-km)计时赛表现和血液电解质浓度的急性影响。
在第一次访问(V1)中,参与者(10 名男性和 10 名女性,年龄 20-35 岁,BMI≤29kg/m,有规律的运动)报告至实验室,进行以下测试:i)身高和体重测量,ii)身体成分分析,iii)跑步机测试以测量最大有氧能力,iv)5-km 计时赛熟悉度。第二次访问(V2)在 V1 一周后的早上(0600-0900)进行,参与者禁食 12-14 小时(不进食或饮水)。第一次评估(V2-T1)包括裸体体重、尿比重(USG)、心境状态问卷(POMS)和视觉模拟量表(VAS)问卷,以量化抽筋。然后检查心率(HR)、血压(BP)、全身水合作用(通过生物电阻抗光谱法[BIS])。最后,通过手指穿刺进行血液标志物测量。参与者在 3 分钟内随机饮用一种饮料(MIDS 16 液盎司、W 16 液盎司或 CE 16 液盎司),然后休息 45 分钟。休息后,进行第二次评估(V2-T2),评估参与者的 USG,完成 POMS 和 VAS 问卷,测量 HR、BP 和血液标志物。然后,参与者进行 5 公里跑步机计时赛。计时赛结束后,参与者立即进行第三次测试(V2-T3),开始时进行血液标志物、HR 和 BP 评估,然后进行裸体体重评估,并进行 POMS 和 VAS 问卷。60 分钟后,进行第四次评估(V2-T4),包括 HR、BP 和血液标志物。安静坐 60 分钟后,进行第五次评估(V2-T5),包括参与者的 USG、POMS 和 VAS 问卷、HR、BP、血液标志物和全身水合作用。第三次访问(V3)和第四次访问(V4)遵循相同的方案,只是饮用不同的随机饮料(CE、MIDS 或 W 16 盎司);所有这些都间隔大约一周。
在 5-km 计时赛完成、5-km 计时赛期间的间接测热结果、USG 或裸体体重测量方面,条件之间没有差异(所有相关统计检验均>0.05)。然而,血钾和钠/钾比值显示出显著的相互作用(<0.05),事后检验表明 MIDS 与其他条件相比,这些值得到了更好的维持。CE(<0.05)和 W 饮料(=0.083)的运动后抽筋发生率较高,与 MIDS 条件相比,运动后抽筋的严重程度也较高(<0.05)。
MIDS 不会影响 5-km 计时赛表现,但与 CE 和 W 饮料相比,对血液电解质和运动后自我报告的抽筋结果有有利影响。