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超越超声不可穿透物体的成像。

Imaging beyond ultrasonically-impenetrable objects.

机构信息

Department of Biomedical Engineering, University of California, Davis, California, USA.

出版信息

Sci Rep. 2018 Apr 10;8(1):5759. doi: 10.1038/s41598-018-23776-7.

Abstract

Ultrasound images are severely degraded by the presence of obstacles such as bones and air gaps along the beam path. This paper describes a method for imaging structures that are distal to obstacles that are otherwise impenetrable to ultrasound. The method uses an optically-inspired holographic algorithm to beam-shape the emitted ultrasound field in order to bypass the obstacle and place the beam focus beyond the obstruction. The resulting performance depends on the transducer aperture, the size and position of the obstacle, and the position of the target. Improvement compared to standard ultrasound imaging is significant for obstacles for which the width is larger than one fourth of the transducer aperture and the depth is within a few centimeters of the transducer. For such cases, the improvement in focal intensity at the location of the target reaches 30-fold, and the improvement in peak-to-side-lobe ratio reaches 3-fold. The method can be implemented in conventional ultrasound systems, and the entire process can be performed in real time. This method has applications in the fields of cancer detection, abdominal imaging, imaging of vertebral structure and ultrasound tomography. Here, its effectiveness is demonstrated using wire targets, tissue mimicking phantoms and an ex vivo biological sample.

摘要

超声图像会因波束路径上存在障碍物(如骨头和空气间隙)而严重劣化。本文描述了一种用于对障碍物后面的结构成像的方法,这些障碍物对超声是不可穿透的。该方法使用受光学启发的全息算法来对发射的超声场进行波束成形,以便绕过障碍物,并将波束焦点置于障碍物之外。所得的性能取决于换能器孔径、障碍物的大小和位置以及目标的位置。对于障碍物的宽度大于换能器孔径的四分之一且深度在换能器几厘米范围内的情况,与标准超声成像相比,该方法的性能显著提高。对于这种情况,目标位置处的焦点强度提高了 30 倍,峰值与旁瓣比提高了 3 倍。该方法可以在传统的超声系统中实现,并且整个过程可以实时执行。该方法在癌症检测、腹部成像、椎体结构成像和超声层析成像等领域有应用。在这里,使用金属丝目标、组织模拟体模和离体生物样本展示了其有效性。

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