Nassiri Nader, Ghorbanhosseini Saeedeh, Jafarzadehpur Ebrahim, Kavousnezhad Sara, Nassiri Nariman, Sheibani Kourosh
Imam Hossein Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Department of Optometry, Iran University of Medical Sciences, Tehran, Iran.
Clin Ophthalmol. 2018 Mar 29;12:601-605. doi: 10.2147/OPTH.S157501. eCollection 2018.
The purpose of this study was to evaluate the visual acuity as well as endothelial cell density (ECD) and polymegathism after iris-fixated lens (Artiflex AC 401) implantation for correction of moderate to high myopia.
In this retrospective cross-sectional study, 55 eyes from 29 patients undergoing iris-fixated lens implantation for correction of myopia (-5.00 to -15.00 D) from 2007 to 2014 were evaluated. Uncorrected visual acuity, best spectacle-corrected visual acuity, refraction, ECD and polymegathism (coefficient of variation [CV] in the sizes of endothelial cells) were measured preoperatively and 6 months postoperatively.
In the sixth month of follow-up, the uncorrected vision acuity was 20/25 or better in 81.5% of the eyes. The best-corrected visual acuity was 20/30 or better in 96.3% of the eyes, and more than 92% of the eyes had a refraction score of ±1 D from the target refraction. The mean corneal ECD of patients before surgery was 2,803±339 cells/mm, which changed to 2,744±369 cells/mm six months after surgery (=0.142). CV in the sizes of endothelial cells before the surgery was 25.7%±7.1% and six months after surgery it was 25.9%±5.4% (=0.857).
Artiflex iris-fixated lens implantation is a suitable and predictable method for correction of moderate to high myopia. There was no statistically significant change in ECD and polymegathism (CV in the sizes of endothelial cells) after 6 months of follow-up.
本研究旨在评估虹膜固定型人工晶状体（Artiflex AC 401）植入矫正中高度近视后的视力、内皮细胞密度（ECD）和细胞大小不均一性。
在这项回顾性横断面研究中，对2007年至2014年期间接受虹膜固定型人工晶状体植入矫正近视（-5.00至-15.00 D）的29例患者的55只眼进行了评估。术前及术后6个月测量未矫正视力、最佳眼镜矫正视力、屈光、ECD和细胞大小不均一性（内皮细胞大小的变异系数[CV]）。
随访第6个月时，81.5%的患眼未矫正视力达到20/25或更好。96.3%的患眼最佳矫正视力达到20/30或更好，超过92%的患眼屈光度数与目标屈光度数相差±1 D。患者术前角膜ECD的平均值为2803±339个细胞/mm²，术后6个月变为2744±369个细胞/mm²（P=0.142）。术前内皮细胞大小的CV为25.7%±7.1%，术后6个月为25.9%±5.4%（P=0.857）。
Artiflex虹膜固定型人工晶状体植入是矫正中高度近视的一种合适且可预测的方法。随访6个月后，ECD和细胞大小不均一性（内皮细胞大小的CV）无统计学显著变化。
