移植受者发热：思考范围应超越感染。
Fever in a transplant recipient: think beyond infection.
作者信息
Kamboj Mayanka, Chornyy Volodymyr, Koratala Abhilash, Santos Alfonso H
机构信息
Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.
出版信息
Clin Case Rep. 2018 Feb 21;6(4):651-652. doi: 10.1002/ccr3.1432. eCollection 2018 Apr.
Abstract
Immune reconstitution inflammatory syndrome (IRIS) is an exaggerated inflammatory cascade initiated in response to immune recovery during the resolution of an infection. Reduction in calcineurin inhibitor levels in organ transplant recipients due to enhanced metabolism from interaction with rifampin can predispose these individuals to develop IRIS during the treatment of tuberculosis and mimic sepsis.
摘要
免疫重建炎症综合征（IRIS）是在感染消退过程中，机体对免疫恢复产生反应而引发的一种过度炎症反应。器官移植受者中，由于与利福平相互作用导致代谢增强，钙调神经磷酸酶抑制剂水平降低，这可能使这些个体在治疗结核病期间易发生IRIS，并表现出脓毒症的症状。
相似文献
1
Fever in a transplant recipient: think beyond infection.移植受者发热：思考范围应超越感染。
Clin Case Rep. 2018 Feb 21;6(4):651-652. doi: 10.1002/ccr3.1432. eCollection 2018 Apr.
2
Treating tuberculosis in solid organ transplant recipients.实体器官移植受者的结核病治疗
Curr Opin Infect Dis. 2014 Dec;27(6):501-5. doi: 10.1097/QCO.0000000000000102.
3
Immune Reconstitution Inflammatory Syndrome and Drug-Induced Liver Injury During Treatment of Disseminated Tuberculosis in a Liver Transplant Recipient: A Case Report.肝移植受者播散性肺结核治疗期间的免疫重建炎症综合征和药物性肝损伤：一例报告
Transplant Proc. 2023 Oct;55(8):1972-1974. doi: 10.1016/j.transproceed.2023.06.007. Epub 2023 Jul 17.
4
Immune Reconstitution Inflammatory Syndrome Occurring in a Kidney Transplant Patient with Extrapulmonary Tuberculosis.一名肾移植患者合并肺外结核发生免疫重建炎症综合征。
Case Rep Transplant. 2017;2017:6290987. doi: 10.1155/2017/6290987. Epub 2017 Mar 7.
5
Reversal of uniocular blindness with corticosteroids in a solid organ transplant recipient with cryptococcal meningitis and immune reconstitution syndrome (IRIS): A case report.器官移植受者并发隐球菌性脑膜炎和免疫重建综合征（IRIS）时，皮质类固醇治疗单眼盲：病例报告。
J Mycol Med. 2023 Aug;33(3):101406. doi: 10.1016/j.mycmed.2023.101406. Epub 2023 May 13.
6
Blastomycosis in a renal transplant recipient: Case of immune reconstitution inflammatory syndrome.肾移植受者的芽生菌病：免疫重建炎症综合征病例
Med Mycol Case Rep. 2018 Mar 1;21:20-22. doi: 10.1016/j.mmcr.2018.02.003. eCollection 2018 Sep.
7
Immune reconstitution inflammatory syndrome mimicking relapsing cryptococcal meningitis in a renal transplant recipient.肾移植受者中模仿复发性隐球菌性脑膜炎的免疫重建炎症综合征。
Transpl Infect Dis. 2011 Jun;13(3):303-8. doi: 10.1111/j.1399-3062.2010.00592.x. Epub 2010 Dec 16.
8
Use of rifabutin for the treatment of a latent tuberculosis infection in a patient after solid organ transplantation.利福布汀治疗实体器官移植后潜伏性结核感染患者。
Liver Transpl. 2013 Apr;19(4):457-61. doi: 10.1002/lt.23622. Epub 2013 Mar 22.
9
Progressive multifocal leukoencephalopathy - immune reconstitution inflammatory syndrome (PML-IRIS) in liver transplant recipient.肝移植受者进行性多灶性白质脑病-免疫重建炎症综合征（PML-IRIS）
Mult Scler Relat Disord. 2017 Oct;17:135-137. doi: 10.1016/j.msard.2017.07.018. Epub 2017 Jul 19.
10
Sequelae of Cryptococcal-Immune Reconstitution Inflammatory Syndrome in a Kidney Transplant Recipient: A Case Report.肾移植受者隐球菌免疫重建炎症综合征的后遗症：一例报告
Can J Kidney Health Dis. 2023 May 5;10:20543581231172399. doi: 10.1177/20543581231172399. eCollection 2023.
本文引用的文献
1
Immune Reconstitution Inflammatory Syndrome Occurring in a Kidney Transplant Patient with Extrapulmonary Tuberculosis.一名肾移植患者合并肺外结核发生免疫重建炎症综合征。
Case Rep Transplant. 2017;2017:6290987. doi: 10.1155/2017/6290987. Epub 2017 Mar 7.
2
Interactions between anti-infective agents and immunosuppressants in solid organ transplantation.实体器官移植中抗感染药物与免疫抑制剂之间的相互作用。
Am J Transplant. 2013 Mar;13 Suppl 4:318-26. doi: 10.1111/ajt.12123.
3
Mycobacterium tuberculosis-associated immune reconstitution syndrome in solid-organ transplant recipients.实体器官移植受者中与结核分枝杆菌相关的免疫重建综合征。
Transplantation. 2013 May 15;95(9):1173-81. doi: 10.1097/TP.0b013e31828719c8.
4
Opportunistic infection-associated immune reconstitution syndrome in transplant recipients.移植受者机会性感染相关免疫重建综合征。
Clin Infect Dis. 2011 Jul 15;53(2):168-76. doi: 10.1093/cid/cir276.
5
Immune reconstitution disease associated with mycobacterial infections in HIV-infected individuals receiving antiretrovirals.接受抗逆转录病毒治疗的HIV感染者中与分枝杆菌感染相关的免疫重建疾病
Lancet Infect Dis. 2005 Jun;5(6):361-73. doi: 10.1016/S1473-3099(05)70140-7.
Zotero 插件