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使用世界卫生组织多中心生长参考研究标准来评估斯里兰卡婴儿的生长参数是否合适?一项单中心横断面研究。

Is it appropriate to use WHO Multicentre Growth Reference Study standards to assess the growth parameters of Sri Lankan babies? A single-centre cross-sectional study.

作者信息

Abeyagunawardena Ishanya Ayeshini, Abeynayake Arundhi, Anuththara Thushani, Alawaththegama Kasun, Amanda Sakuni, Abeyrathne Vishaka, Amaradasa Prabhadi, Anuradha Buddhika, Ahmed Hanan, Abeykoon Chathupa, Fernando Dinesh Malcolm Gerard

机构信息

Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka.

Department of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka.

出版信息

BMJ Paediatr Open. 2018 Feb 6;2(1):e000174. doi: 10.1136/bmjpo-2017-000174. eCollection 2018.

Abstract

OBJECTIVE

To compare the anthropometric measurements of newborns in a tertiary care hospital in Sri Lanka, with WHO standards.

METHODS

Birth weight, length and occipitofrontal circumference (OFC) of 400 consecutive, term newborns of healthy mothers were measured in a tertiary care hospital.

RESULTS

400 subjects were approached and seven were excluded, concluding the study population to 184 boys and 209 females. Medians of birth weight, length and OFC were 3000 g, 49.95 cm and 34.15 cm of males and IQRs were 555.00, 2.70 and 1.70, respectively. For females, the medians of birth weight, length and OFC were 2900 g, 48.9 cm and 34.00 cm with IQRs of 450.00, 2.70 and 1.50, respectively. The two-tailed t-test revealed that median weights of males (t=9.632) and females (t=12.04) and OFC of males (t=3.98) were significantly lower than the WHO medians. There was a significant association of birth weight, with mother's prepregnancy weight, in males (β coefficient=12.629 with 95% CI 6.275 to 18.982) and females (β coefficient=5.880, 95% CI 1.434 to 10.325). Significant associations of length (β coefficient=0.046, 95% CI 0.012 to 0.080) and OFC (β coefficient=0.033, 95% CI 0.014 to 0.053) with mother's prepregnancy weight in males and length (β coefficient=0.084, 95% CI 0.022 to 0.145) and weight (β coefficient=10.780, 95% CI 0.93 to 20.629) with maternal age in females were found. Furthermore, birth weight in males was significantly associated with maternal height (β coefficient=10.899, 95% CI 0.552 to 21.247). Education level, ethnicity and parity showed no significant associations with above parameters.

CONCLUSION

The median weights of both sexes and OFC in males were significantly lower than the WHO standards. Island-wide studies are indicated to evaluate the appropriateness of applying WHO standards to Sri Lankan newborns.

摘要

目的

将斯里兰卡一家三级护理医院新生儿的人体测量数据与世界卫生组织(WHO)的标准进行比较。

方法

在一家三级护理医院对400名连续的、母亲健康的足月儿新生儿的出生体重、身长和枕额周长(OFC)进行测量。

结果

共接触了400名受试者,排除了7名,最终研究人群为184名男性和209名女性。男性出生体重、身长和OFC的中位数分别为3000g、49.95cm和34.15cm,四分位间距分别为555.00、2.70和1.70。女性出生体重、身长和OFC的中位数分别为2900g、48.9cm和34.00cm,四分位间距分别为450.00、2.70和1.50。双尾t检验显示,男性(t=9.632)和女性(t=12.04)的体重中位数以及男性的OFC(t=3.98)均显著低于WHO的中位数。男性出生体重与母亲孕前体重存在显著关联(β系数=12.629,95%置信区间为6.275至18.982),女性也存在显著关联(β系数=5.880,95%置信区间为1.434至10.325)。男性身长(β系数=0.046,95%置信区间为0.012至0.080)和OFC(β系数=0.033,95%置信区间为0.014至0.

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Synthetic growth reference charts.合成生长参考图表。
Am J Hum Biol. 2016 Jan-Feb;28(1):98-111. doi: 10.1002/ajhb.22759. Epub 2015 Jun 30.

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