Wang Ming, Jiang Xuefeng
School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, People's Republic of China.
Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, People's Republic of China.
Top Curr Chem (Cham). 2018 Apr 10;376(2):14. doi: 10.1007/s41061-018-0192-5.
Disulfide, as a common structural motif, has been frequently used in pharmaceuticals, nature products, and chemical biology. This chapter focuses on the methodologies that were reported recently for the synthesis of disulfide-containing compounds with particular emphasis on the synthesis of unsymmetrical disulfides. The presentation is organized according to the structure of the disulfides and the synthetic method.
二硫键作为一种常见的结构基序,已在药物、天然产物和化学生物学中频繁使用。本章重点介绍了最近报道的用于合成含二硫键化合物的方法,特别强调了不对称二硫键的合成。内容根据二硫键的结构和合成方法进行编排。