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妊娠期和哺乳期使用长效奥氮平注射剂:病例报告。

Long-acting olanzapine injection during pregnancy and breastfeeding: a case report.

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Southern Stockholm Psychiatric Clinic, Stockholm, Sweden.

出版信息

Arch Womens Ment Health. 2018 Oct;21(5):587-589. doi: 10.1007/s00737-018-0840-3. Epub 2018 Apr 10.

Abstract

We present one case of a woman treated with the intramuscular depot formulation of the atypical antipsychotic, olanzapine pamoate (ZypAdhera®), during pregnancy and breastfeeding. Data on olanzapine distribution in breast milk as well as on plasma concentration in the nursed infant are provided. The present case report demonstrates that olanzapine was excreted in the breast milk, but the breast-fed infant had very low olanzapine concentrations, which did not result in any adverse effects.

摘要

我们报告了一例女性在怀孕期间和哺乳期使用肌肉注射长效制剂奥氮平癸酸酯(再普乐®)进行治疗的案例。提供了奥氮平在母乳中分布的数据以及哺乳期婴儿的血浆浓度数据。本病例报告表明奥氮平可分泌至母乳中,但母乳喂养的婴儿中奥氮平浓度非常低,并未产生任何不良影响。

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