Wójtowicz Rafał, Krawiec Magdalena, Orlicz Piotr
Department of Anaesthesiology and Intensive Care, Central Teaching Hospital in Warsaw, Ministry of Interior and Administration (MI&A), Poland.
Anaesthesiol Intensive Ther. 2018;50(1):34-39. doi: 10.5603/AIT.2018.0006.
The aim of this article is to conduct an overview of the current state of knowledge about patients presenting anti-Nmethyl- D-aspartate receptor encephalitis associated with neoplastic process, as well as diagnosis and treatment. This disease concerns mainly young women and correlates with ovarian teratoma. Most important problems seems to be the difficulties in making a proper diagnosis ensuing from the rarity of this syndrome, the period from the appearance the first symptoms to starting treatment and the correct handling of intensive care complications. There are only a few articles describing severe, complicated cases of this type of encephalitis, requiring treatment in an intensive care unit.
本文旨在对与肿瘤相关的抗N-甲基-D-天冬氨酸受体脑炎患者的当前知识现状以及诊断和治疗进行综述。这种疾病主要影响年轻女性,且与卵巢畸胎瘤相关。最重要的问题似乎是由于该综合征罕见,从出现首发症状到开始治疗的时间间隔,以及对重症监护并发症的正确处理,导致难以做出准确诊断。仅有少数文章描述了这类需要在重症监护病房进行治疗的严重、复杂型脑炎病例。