Cell Biology Program, Research Institute, Hospital for Sick Children , Toronto, Ontario , Canada.
Department of Biochemistry, University of Toronto , Toronto, Ontario , Canada.
Physiology (Bethesda). 2018 May 1;33(3):225-234. doi: 10.1152/physiol.00005.2018.
Blood platelets are involved in a wide range of physiological responses and pathological processes. Recent studies have considerably advanced our understanding of the mechanisms of platelet production and clearance, revealing new connections between the birth and death of these tiny, abundant cells. Key insights have also been gained into how physiological challenges such as inflammation, infection, and chemotherapy can affect megakaryocytes, the cells that produce platelets.
血小板参与广泛的生理反应和病理过程。最近的研究极大地提高了我们对血小板生成和清除机制的理解，揭示了这些微小而丰富的细胞诞生和死亡之间的新联系。人们还深入了解了炎症、感染和化疗等生理挑战如何影响产生血小板的巨核细胞。
