电休克治疗对抑郁症患者内啡肽的影响。
The effect of electroconvulsive therapy on endorphins in depression.
作者信息
Ghadirian A M, Gianoulakis C, Nair N P
机构信息
Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
出版信息
Biol Psychiatry. 1988 Mar 1;23(5):459-64. doi: 10.1016/0006-3223(88)90017-0.
The time course study of the endorphin response to electroconvulsive therapy (ECT) was carried out in 10 patients (including one control who did not receive active ECT) at the first and sixth ECT. Results showed a significant rise of plasma endorphin levels after ECT. This increase returned to the pre-ECT level within 1 hr after ECT. There was a pre-rise of plasma endorphin level, which probably was stress related and which was also observed in the control case.
在10名患者（包括1名未接受有效电休克治疗的对照者）接受首次和第六次电休克治疗时，开展了内啡肽对电休克治疗（ECT）反应的时间进程研究。结果显示，电休克治疗后血浆内啡肽水平显著升高。这种升高在电休克治疗后1小时内恢复到治疗前水平。血浆内啡肽水平存在预升高情况，这可能与应激有关，且在对照病例中也观察到了这种情况。
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