Saeed Mohd, Faisal Syed Mohd, Ahmad Irfan, Kausar Mohd Adnan, Alam Md Jahoor, Khan Saif, Mustafa Huma
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail, KSA.
Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, UP-202002, India.
Cell Mol Biol (Noisy-le-grand). 2018 Mar 31;64(4):46-51.
Lymphatic filariasis (LF) is a chronic and debilitating disease that affects people in tropical and sub-tropical areas of Asia, Africa, and Western Pacific. It is one of the leading community health problems in some of the endemic districts in India including Hardoi district of Uttar Pradesh. The disease is caused by the parasites Wuchereria bancrofti (W. bancrofti), Brugia malayi (B. malayi) and Brugia timori (B. timori), transmitted by the vector Culex, Anopheles and other mosquitoes. This cross-sectional survey study was carried out in rural areas, where its inhabitants vary in socio-economic status, from low to middle-income class. 12 villages of Hardoi district, Uttar Pradesh, India were included. The aim was to see the impact of age and gender on various clinical forms of LF and in estimating its economic and social implications. 260 LF affected people in different parts of Hardoi district were surveyed. The results revealed that the Mass Drug Administration (MDA) coverage reached more than 90%. The overall Microfilaria rate had been reduced, however the prevalence of elephantiasis increased with the progression of age and was found to be highest among people of >70 years of age, regardless of their gender.
淋巴丝虫病是一种慢性致残性疾病，影响亚洲、非洲和西太平洋热带及亚热带地区的人群。它是印度一些流行地区（包括北方邦哈多伊区）主要的社区健康问题之一。该疾病由班氏吴策线虫、马来布鲁线虫和帝汶布鲁线虫寄生虫引起，通过库蚊、按蚊和其他蚊子传播。这项横断面调查研究在农村地区开展，当地居民社会经济地位各异，涵盖低收入到中等收入阶层。印度北方邦哈多伊区的12个村庄被纳入研究。目的是观察年龄和性别对淋巴丝虫病各种临床形式的影响，并评估其经济和社会影响。对哈多伊区不同地区的260名淋巴丝虫病患者进行了调查。结果显示，群体服药（MDA）覆盖率超过90%。总体微丝蚴率有所降低，然而，象皮肿患病率随年龄增长而上升，在70岁以上人群中无论性别均为最高。
