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高锰酸钾颗粒导致的眼外伤

Ocular Injury due to Potassium Permanganate Granules.

作者信息

Chirapapaisan Chareenun, Prabhasawat Pinnita, Srivannaboon Sabong, Roongpoovapatr Vatookarn, Chitsuthipakorn Piyada

机构信息

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Department of Ophthalmology, Mettapracharak (Wat Raikhing) Hospital, Bangkok, Thailand.

出版信息

Case Rep Ophthalmol. 2018 Feb 8;9(1):132-137. doi: 10.1159/000486922. eCollection 2018 Jan-Apr.

Abstract

PURPOSE

We report a rare case of ocular injury due to potassium permanganate (KMnO) granules in a child.

METHODS

This is a retrospective case report.

RESULTS

A 2-year-old boy was transferred to our emergency room with severe pain in his right eye, inflamed eyelids, and brownish stains on his fingers. Chemical injury was suspected. Copious eye irrigation was immediately performed. Diffuse brownish splotches were then observed at the inferior bulbar conjunctiva. Otherwise, systemic organs were intact. Complete eye exam under general anesthesia revealed a 5-mm epithelial defect at the central cornea, along with generalized conjunctival injection and limbal ischemia, inferiorly. Multiple semi-dissolved granules of KMnO trapped in the inferior fornix were identified. The chemical particles were gradually washed out and removed; however, the brownish stains remained. The patient received preservative-free steroid, antibiotic eye drops, and lubricants as regular management for mild to moderate degree of ocular burn. Pseudomembrane developed early and transformed into symblepharon within a few days after the injury. Membrane adhesion was lysed, and more aggressive medications were then substituted. Commercial amniotic membrane (PROKERA®) was also applied to promote wound healing and to prevent recurrence of symblepharon. The ocular surface was eventually restored, and corneal transparency was preserved.

CONCLUSION

Ocular injury with the granular form of KMnO is rare. Its toxicity is comparable to concentrated KMnO solution. However, the dissolved particles that had been absorbed in the stained conjunctiva were continuously released and damaged the ocular surface more than we primarily anticipated. Awareness of this condition and prompt management yield a good treatment outcome.

摘要

目的

我们报告一例儿童因高锰酸钾(KMnO)颗粒导致眼外伤的罕见病例。

方法

这是一篇回顾性病例报告。

结果

一名2岁男孩被转诊至我们的急诊室,右眼剧痛、眼睑发炎,手指有褐色污渍。怀疑有化学伤。立即进行了大量眼部冲洗。随后在下睑结膜观察到弥漫性褐色斑点。其他全身器官完好。全身麻醉下的全面眼部检查显示中央角膜有一个5毫米的上皮缺损,伴有结膜充血和下方角膜缘缺血。在下穹窿部发现多个半溶解的KMnO颗粒。化学颗粒逐渐被冲洗掉并清除;然而,褐色污渍仍然存在。患者接受了无防腐剂的类固醇、抗生素眼药水和润滑剂,作为轻度至中度眼烧伤的常规治疗。伤后早期出现假膜,并在几天内转变为睑球粘连。松解了膜粘连,随后更换了更积极的药物。还应用了商用羊膜(PROKERA®)来促进伤口愈合并防止睑球粘连复发。眼表最终恢复,角膜透明度得以保留。

结论

KMnO颗粒形式导致的眼外伤很少见。其毒性与浓KMnO溶液相当。然而,已被染色结膜吸收的溶解颗粒持续释放,对眼表造成的损害比我们最初预期的更大。认识到这种情况并及时处理可取得良好的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70e8/5892315/c029ab051449/cop-0009-0132-g01.jpg

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