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高锰酸钾中毒:一例气道管理困难及肝损伤的罕见病例。

Potassium permanganate toxicity: A rare case with difficult airway management and hepatic damage.

作者信息

Agrawal Vijay Kumar, Bansal Abhishek, Kumar Ranjeet, Kumawat Bhanwar Lal, Mahajan Parul

机构信息

Department of Critical Care Medicine and Pulmonology, Metro Heart Institute with Multispeciality, Sector 16A, Faridabad, Haryana, India.

出版信息

Indian J Crit Care Med. 2014 Dec;18(12):819-21. doi: 10.4103/0972-5229.146318.

Abstract

Potassium permanganate (KMnO4) is rarely used for suicidal attempt. Its ingestion can lead to local as well as systemic toxicities due to coagulation necrosis and damage, caused by free radicals of permanganate. We recently managed a case of suicidal ingestion of KMnO4 in a lethal dose. She had significant narrowing of upper airway leading to difficult intubation as well as hepatic dysfunction and coagulopathy as systemic manifestation. We suggest to keep ourselves ready to handle difficult airway with the aid of fiber optic bronchoscope or surgical airway management in such patients. Upper gastrointestinal (GI) endoscopy should be done at the earliest to determine the extent of upper GI injury and further nutrition planning.

摘要

高锰酸钾(KMnO4)很少被用于自杀企图。由于高锰酸根自由基引起的凝固性坏死和损伤,摄入它会导致局部和全身毒性。我们最近处理了一例摄入致死剂量KMnO4的自杀病例。她的上呼吸道明显狭窄,导致插管困难,同时还出现了肝功能障碍和凝血功能障碍等全身表现。我们建议在这类患者中,借助纤维支气管镜或手术气道管理,随时准备应对困难气道。应尽早进行上消化道(GI)内镜检查,以确定上消化道损伤的程度并制定进一步的营养计划。

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本文引用的文献

1
Suicidal ingestion of potassium permanganate.自杀性吞服高锰酸钾。
World J Emerg Med. 2013;4(1):73-4. doi: 10.5847/wjem.j.issn.1920-8642.2013.01.014.
2
Unintentional ingestion of potassium permanganate.意外摄入高锰酸钾。
Pediatr Emerg Care. 2004 Mar;20(3):185-187. doi: 10.1097/01.pec.0000117926.65522.33.
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Airway obstruction following potassium permanganate ingestion.摄入高锰酸钾后气道阻塞。
Anaesthesia. 2003 Jun;58(6):606-7. doi: 10.1046/j.1365-2044.2003.03207_12.x.
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Hum Toxicol. 1986 Dec;5(6):393-4. doi: 10.1177/096032718600500613.
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Ingestion of potassium permanganate crystals by a three-year-old boy.
Med J Aust. 1987 Jun 15;146(12):639-40. doi: 10.5694/j.1326-5377.1987.tb120444.x.

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