Razzaque A, Da Vanzo J, Rahman M, Gausia K, Hale L, Khan M A, Mustafa A H M G
ICDDR, B: Centre for Health and Population Research, Public Health Sciences Division, Mohakhali, Dhaka, Bangladesh.
Australia National University, Canberra, Australia.
Int J Gynaecol Obstet. 2005 Apr;89 Suppl 1:S41-S49. doi: 10.1016/j.ijgo.2005.01.003.
The study examines the relationship between pregnancy spacing and seven measures of maternal morbidity in Matlab, Bangladesh.
The study analyzes maternal morbidity data on 11,122 women who visited a health center during their third trimester of pregnancy between 1996 and 2002. Adjusted odds ratios were obtained through logistic regression analysis to assess the effects of pregnancy intervals of differing lengths while holding constant other influences (six variables) on maternal morbidity.
After controlling these variables, pre-eclampsia and high blood pressure are significantly more likely for women with preceding inter-pregnancy intervals of less than 6 months or 75 months or more compared to those with intervals of 27-50 months. Premature rupture of membranes is significantly more likely following inter-pregnancy intervals of 6-14 months, and edema is significantly more likely following inter-pregnancy intervals over 50 months.
Short and long inter-pregnancy intervals are associated with increased incidence of some maternal morbidities.
本研究考察了孟加拉国马特莱地区妊娠间隔与七种孕产妇发病指标之间的关系。
该研究分析了1996年至2002年期间在妊娠晚期前往健康中心就诊的11122名妇女的孕产妇发病数据。通过逻辑回归分析获得调整后的比值比，以评估不同长度妊娠间隔对孕产妇发病的影响，同时保持其他影响因素（六个变量）不变。
在控制这些变量后，与妊娠间隔为27 - 50个月的妇女相比，妊娠前间隔小于6个月或75个月及以上的妇女患先兆子痫和高血压的可能性显著更高。妊娠间隔为6 - 14个月后胎膜早破的可能性显著更高，妊娠间隔超过50个月后水肿的可能性显著更高。
妊娠间隔过短和过长均与某些孕产妇发病率的增加有关。
