Hando Tamotsu, Ohno Masaguki, Kurose Takaaki
Department of Perinato-Gynecology, Kagawa Medical University, Faculty of Medicine Japan.
Int J Gynaecol Obstet. 1998 Apr;60 Suppl 1:S71-S76. doi: 10.1016/S0020-7292(98)80008-8.
The regional registration in 11 prefectures and one area covering 34% of total Japanese population started in 1974, increasing gradually to 21 prefectures and one area in 1993 covering 48.5% of total Japanese populations, by the Japan Trophoblastic Disease Committee under the auspices of Japan Society of Obstetrics and Gynecology. The results showed marked decreasing trend in incidence of molar pregnancy and choriocarcinoma in Japan. The most frequent antecedent pregnancies of choriocarcinoma has shifted from molar pregnancy in 1974 to term pregnancy in 1993. The Choriocarcinoma Risk Score Table that is in use and of practical significance, differentiating choriocarcinoma from invasive or metastatic mole by reference to simple 8 clinical items with the probability of more than 90% when compared with the histological diagnoses, is also presented.
1974年，在日本妇产科学会的支持下，日本滋养细胞疾病委员会开始在11个 prefectures 和1个地区进行区域登记，这些地区覆盖了日本总人口的34%，到1993年逐渐增加到21个 prefectures 和1个地区，覆盖了日本总人口的48.5%。结果显示，日本葡萄胎和绒毛膜癌的发病率呈明显下降趋势。绒毛膜癌最常见的既往妊娠情况已从1974年的葡萄胎转变为1993年的足月妊娠。文中还介绍了目前正在使用且具有实际意义的绒毛膜癌风险评分表，该表通过参考8项简单的临床指标，将绒毛膜癌与侵袭性或转移性葡萄胎区分开来，与组织学诊断相比，其准确率超过90%。 （注：prefectures这个词在文中未明确中文释义，可根据上下文理解为日本的一级行政区“县”之类的意思 ）
