Walter M, Brenner U, Holzmüller W, Müller J M
Chirurgischen Universitätsklinik Köln-Lindenthal, BRD.
Z Exp Chir Transplant Kunstliche Organe. 1987;20(6):328-33.
A preparation procedure by making of biologic implants in their biologic texture was investigated in using closures of abdominal wall defects. Defects of the ventral trunk wall of 10 to 20 cm dimension were closed with a collagen implant of the equal size. The morphologic investigation was carried out after 12 respectively 24 months. The kind of the immigrated cells, the revascularisation, and the integration of the implants were criteria for the reutilization. Exclusive fibrocytes with regular cell density in the whole implant were provable after 12 months. The revascularization was demonstrable by numerous vessels and capillaries. The light-histologic findings were unchanged after 24 months, a distinction between implant and surrounding tissue was possible only in an electro-optical way.
研究了一种通过制作具有生物质地的生物植入物来修复腹壁缺损的制备方法。用尺寸相同的胶原植入物修复10至20厘米大小的躯干前壁缺损。分别在12个月和24个月后进行形态学研究。植入物中移入细胞的种类、血管再生情况以及植入物的整合情况是判断其能否再次利用的标准。12个月后，在整个植入物中可证实仅存在细胞密度正常的成纤维细胞。通过大量血管和毛细血管可证明血管再生情况。24个月后光镜组织学检查结果无变化，只有通过电子光学方法才能区分植入物和周围组织。
