Reigel M M, Hollier L H, Pairolero P C, Hallett J W
Section of Vascular Surgery, Mayo Clinic, Rochester, Minnesota 55905.
Am Surg. 1988 Mar;54(3):134-6.
Standard knitted Dacron prosthetic grafts in the aortic position have performed well in terms of patency and durability, but require preclotting and lose their pliability with use. In an effort to overcome these problems, a collagen-impregnated double-velour knitted Dacron graft has been developed. This graft is impervious to blood, does not require preclotting, and maintains its pliability. During a 2 and one half year period, 590 of these grafts have been used at our institution for abdominal aortic replacement in both emergent and elective cases. Indications have included aneurysmal disease (67%), occlusive disease (30%), and failed previous aortic graft (3%). A bifurcated graft has been used in most cases (68%). The patient population has included 449 men and 141 women. Their median age is 68 years, with a range from 15 to 91 years. Seventy nine per cent of the patients experienced no perioperative complications. The remaining twenty one per cent have had a variety of complications, most of them cardiac or pulmonary, but none related directly to the graft. Twenty nine patients died in the perioperative period, for a mortality of 4.9 per cent. Late complications have been infrequent and in no cases directly related to the graft. There have been no graft-related late deaths. It is concluded that, at least in this early experience, there are no problems inherent in the use of this graft. Its pliability and the fact that it does not require preclotting are distinct advantages over previous Dacron grafts.
标准针织涤纶人工血管用于主动脉部位时，在通畅性和耐用性方面表现良好，但需要预凝，且使用后会失去柔韧性。为克服这些问题，已研发出一种含胶原蛋白的双面绒针织涤纶人工血管。这种人工血管不透血，无需预凝，并能保持其柔韧性。在两年半的时间里，我们机构已将590根这种人工血管用于急诊和择期的腹主动脉置换手术。适应证包括动脉瘤性疾病（67%）、闭塞性疾病（30%）和既往主动脉人工血管失效（3%）。大多数情况下（68%）使用的是分叉人工血管。患者群体包括449名男性和141名女性。他们的年龄中位数为68岁，范围从15岁到91岁。79%的患者未发生围手术期并发症。其余21%出现了各种并发症，其中大多数是心脏或肺部并发症，但均与人工血管无直接关联。29名患者在围手术期死亡，死亡率为4.9%。晚期并发症很少见，且在任何情况下都与人工血管无直接关系。没有与人工血管相关的晚期死亡病例。结论是，至少在这一早期经验中，使用这种人工血管不存在固有的问题。与先前的涤纶人工血管相比，其柔韧性以及无需预凝这一事实是明显的优势。
