Romero R, Snyder E, Scott D, Oyarzun E, Hobbins J C, Duffy T P
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06510.
Am J Perinatol. 1988 Apr;5(2):109-12. doi: 10.1055/s-2007-999667.
Platelet activation has been implicated in the pathogenesis of several obstetrical conditions such as preeclampsia and intrauterine growth retardation. Plasma beta-thromboglobulin (BTG) concentration is an index of in vivo platelet activation. The purpose of this study was to establish normal values of plasma BTG during pregnancy, labor and puerperium. Plasma BTG concentrations were determined from 121 uncomplicated pregnant women, 20 women in labor, 20 puerperal women, and a control group of 28 healthy non-pregnant volunteers. There was no significant difference in plasma BTG concentrations between non-pregnant and pregnant women. Gestational age, labor, and puerperium did not affect plasma BTG concentrations.
血小板活化与几种产科疾病的发病机制有关，如先兆子痫和胎儿宫内生长受限。血浆β-血小板球蛋白（BTG）浓度是体内血小板活化的一个指标。本研究的目的是确定孕期、分娩期及产褥期血浆BTG的正常值。测定了121例无并发症孕妇、20例分娩期妇女、20例产褥期妇女以及28名健康非孕志愿者对照组的血浆BTG浓度。非孕妇女和孕妇的血浆BTG浓度无显著差异。孕周、分娩和产褥期均不影响血浆BTG浓度。
