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儿科卒中的流行病学、危险因素和特征:一项全国范围内基于人群的研究。

Epidemiology, risk factors and characteristics of pediatric stroke: a nationwide population-based study.

机构信息

From the Department of Pediatrics, Kuang-Tien General Hospital, No. 117, Shatian Road Shalu District, Taichung City 43302.

Department of Nutrition, Hungkuang University, No. 1018, Sec. 6, Taiwan Boulevard, Shalu District, Taichung City 43302.

出版信息

QJM. 2018 Jul 1;111(7):445-454. doi: 10.1093/qjmed/hcy066.

DOI:10.1093/qjmed/hcy066
PMID:29648667
Abstract

BACKGROUND

Stroke, classically characterized as an acute acquired neurological deficit, is an important leading cause of death and chronic morbidity in children.

AIMS

This study reported the period prevalence, incidence and risk factors of pediatric stroke in Taiwan.

METHODS AND PROCEDURES

All Taiwan inhabitants aged 1 month to 18 years registered in the National Health Insurance Research Database between 2010 and 2011 were enrolled in this study. Factors including age, sex, location and household income levels were collected. Incidence, period prevalence, mortality rate and the possible risks were completely evaluated. Outcomes and results: Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke (27.6% vs. 10.2%, P<0.05). Risk factors or underlying diseases for stroke were identified in 77.8% of the patients and 16.2% had more than one risk factor. The most common risk factors were vascular diseases (26.3%), infection (14.0%) and cardiac disorders (9.1%).

CONCLUSIONS AND IMPLICATIONS

Infants younger than 2 years, boys and children in lower socioeconomic status have a significantly higher risk of stroke. Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke. More than half of the children with stroke had underlying diseases and the causes of hemorrhagic stroke are significantly different from ischemic stroke.

摘要

背景

中风,经典地表现为急性获得性神经功能缺损,是儿童死亡和慢性发病的重要主要原因。

目的

本研究报告了台湾儿科中风的时期患病率、发病率和危险因素。

方法和程序

本研究纳入了 2010 年至 2011 年期间在全民健康保险研究数据库中登记的年龄在 1 个月至 18 岁的所有台湾居民。收集了年龄、性别、地点和家庭收入水平等因素。完全评估了发病率、时期患病率、死亡率和可能的风险。

结果

出血性中风的死亡率明显高于缺血性中风(27.6%比 10.2%,P<0.05)。77.8%的患者存在中风的危险因素或基础疾病,16.2%的患者存在多种危险因素。最常见的危险因素是血管疾病(26.3%)、感染(14.0%)和心脏疾病(9.1%)。

结论和意义

2 岁以下的婴儿、男孩和社会经济地位较低的儿童中风风险显著更高。出血性中风的死亡率明显高于缺血性中风。超过一半的中风患儿有基础疾病,出血性中风的病因与缺血性中风明显不同。

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