Epidemiology, risk factors and characteristics of pediatric stroke: a nationwide population-based study.

BACKGROUND

Stroke, classically characterized as an acute acquired neurological deficit, is an important leading cause of death and chronic morbidity in children.

AIMS

This study reported the period prevalence, incidence and risk factors of pediatric stroke in Taiwan.

METHODS AND PROCEDURES

All Taiwan inhabitants aged 1 month to 18 years registered in the National Health Insurance Research Database between 2010 and 2011 were enrolled in this study. Factors including age, sex, location and household income levels were collected. Incidence, period prevalence, mortality rate and the possible risks were completely evaluated. Outcomes and results: Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke (27.6% vs. 10.2%, P<0.05). Risk factors or underlying diseases for stroke were identified in 77.8% of the patients and 16.2% had more than one risk factor. The most common risk factors were vascular diseases (26.3%), infection (14.0%) and cardiac disorders (9.1%).

CONCLUSIONS AND IMPLICATIONS

Infants younger than 2 years, boys and children in lower socioeconomic status have a significantly higher risk of stroke. Hemorrhagic stroke has a significantly higher mortality rate than ischemic stroke. More than half of the children with stroke had underlying diseases and the causes of hemorrhagic stroke are significantly different from ischemic stroke.