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住院姑息治疗对临终关怀质量和下游急性及康复期医疗利用的影响。

Impact of Inpatient Palliative Care on Quality of End-of-Life Care and Downstream Acute and Postacute Care Utilization.

机构信息

1 Geriatric Palliative Care, Kaiser Permanente Southern California, Los Angeles Medical Center , Los Angeles, California.

2 Geriatric Palliative Care, Kaiser Permanente Southern California, West Los Angeles Medical Center , Los Angeles, California.

出版信息

J Palliat Med. 2018 Jul;21(7):913-923. doi: 10.1089/jpm.2017.0275. Epub 2018 Mar 13.

DOI:10.1089/jpm.2017.0275
PMID:29649400
Abstract

BACKGROUND

Additional evidence is needed regarding the impact of inpatient palliative care (IPC) on the quality of end-of-life care and downstream utilization.

AIM

Examine the effects of IPC on quality of end-of-life care and acute and postacute care use in a large integrated system.

DESIGN

Retrospective cohort design.

SETTING/PARTICIPANTS: Adult decedents from January 1, 2012, to December 31, 2014, who had at least one hospitalization at 11 Kaiser Permanente Southern California medical centers in the 12 months before death and not hospitalized for a trauma-related condition or receiving home-based PC or hospice were included in the cohort.

MATERIALS AND METHODS

Inverse probability of treatment weighting of propensity scores was used to compare outcomes between patients exposed to IPC (n = 3742) and controls (n = 12,755) who never received IPC before death.

RESULTS

Patients who received IPC were more likely to enroll in home-based PC or hospice (69% vs. 43%) and were less likely to die in a hospital (15% vs. 29%) or intensive care (2% vs. 9%) compared with controls (all, p < 0.001). IPC exposure was associated with higher risk for rehospitalization (HR: 1.18, 95% CI 1.11-1.25) and more frequent emergency department visits (RR: 1.16, 95% CI 1.07-1.26) with no increase in postacute care use compared with controls. Stratified analyses showed that IPC effects on acute care utilization were dependent on code status.

CONCLUSION

IPC exposure was associated with higher enrollment in home-based PC/hospice and more deaths at home. The increased acute care utilization by the IPC group may reflect persistent confounding by indication.

摘要

背景

需要更多证据来证明住院姑息治疗(IPC)对临终护理质量和下游利用的影响。

目的

在一个大型综合系统中,研究 IPC 对临终护理质量以及急性和亚急性护理使用的影响。

设计

回顾性队列设计。

设置/参与者:纳入 2012 年 1 月 1 日至 2014 年 12 月 31 日期间至少在加利福尼亚州南部 11 个 Kaiser Permanente 医疗中心住院一次,且在死亡前 12 个月内没有因创伤相关疾病住院、没有接受家庭为基础的姑息治疗或临终关怀的成人死者。

材料和方法

采用倾向评分逆概率治疗加权法比较接受 IPC 治疗的患者(n=3742)与生前从未接受过 IPC 治疗的对照组(n=12755)之间的结局。

结果

与对照组相比,接受 IPC 治疗的患者更有可能接受家庭为基础的姑息治疗或临终关怀(69%比 43%),且更不可能在医院(15%比 29%)或重症监护病房(2%比 9%)死亡(均,p<0.001)。与对照组相比,IPC 暴露与更高的再住院风险(HR:1.18,95%CI 1.11-1.25)和更频繁的急诊就诊(RR:1.16,95%CI 1.07-1.26)相关,但与对照组相比,亚急性护理使用没有增加。分层分析显示,IPC 对急性护理利用的影响取决于代码状态。

结论

IPC 暴露与更高的家庭为基础的姑息治疗/临终关怀的登记率以及更多的在家中死亡相关。IPC 组急性护理利用率的增加可能反映了持续存在的指标性混杂。

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